Integrative Neuroscience

Research includes:

Addiction
Aggresome
Alzheimer's Disease
Amyloid
Amyloid Plaques
Amyotrophic Lateral Sclerosis
Axonal Growth
Axonal Transport
Behavior
Behavioral Neuroscience
Central Nervous System
Dopamine
Drug Abuse
Feeding Behavior

Genetic Engineering
Ingestive Behavior
Lewy Bodies
Mental Illness
Mitochondria
Molecular Neuropharmacology
Molecular Psychiatry
Neural Development
Neurodegeneration
Neurofibrillary Tangles
Neurofilament
Neuron-glia Interactions
Neurons
Neuropsychopharmacology

Oxidative Stress
Parkinson's Disease
Peripherin
Pharmacology
Protein Aggregation
Regulatory Behavior
Sensory System Neurobiology (emphasis on the auditory and vestibular systems)
Substance Abuse
Substantia Nigra
Superoxide Dismutase
Synuclein
Tyrosine Hydroxlase

Training Group Mission:

Neuroscience is a truly integrative discipline as evidenced by the fact that faculty in this program are drawn from approximately 10 departments representing 5 schools at Purdue University. Both the breadth and depth of the research programs among the Purdue faculty span the nervous systems of diverse species, e.g. fruit flies, zebra fish, mice, rats, and humans. Further, the research approach among these systems spans the molecular, cellular, physiological, and behavioral levels of analysis. Students enter the program from diverse undergraduate majors, with equally diverse research interests, and consequently receive training across the levels of analysis required to effectively understand the nervous system and its function. One of the special aspects of the Neuroscience Program is that the participating faculty are drawn from departments and schools within Purdue University not typically associated with training in the life sciences. This inherent diversity in the problem areas and technical approaches taken will offer students from other training programs within PULSe this broad perspective in a way that is relevant to their own disciplines and research.

Faculty Membership

Faculty

Research Area

Aguilar, Ruben C

Protein trafficking and membrane transport in relation to the processes of cell polarity establishment and carcinogenic transformation

Anderson, Joseph M.

Plant host-viral interactions; identification, characterization of molecular markers for resistance genes; cellular and functional genomics

Barker, Eric L.

Molecular pharmacology of antidepressant- and cocaine-sensitive serotonin transporters; endogenous cannabinoid transport

Bartlett, Edward L.

Central auditory neurophysiology and neuroanatomy at the systems and cellular levels

Bharadwaj, Hari

Systems Neuroscience of Audition, Human Neuroimaging and Electrophysiology, Phenomenological and Biophysical Models of Auditory Computations, Sensorineural Hearing Loss, Auditory Processing Disorders, Autism

Bowman, Aaron

Gene x Environment Interactions in Neurological Disease; Metal Neurotoxicity (manganese, methylmercury, copper); Huntington’s Disease, Parkinson’s Disease, Alzheimer’s Disease, Neurodevelopmental disorders

Brewster, Amy

Behavorial Neuroscience

Cannon, Jason

Neurodegeneration, neurotoxicology, Parkinson's disease

Chester, Julia A.

Identification of genetic, neurobiological, and environmental factors that contribute to alcohol drinking and the development of alcoholism

Chopra, Gaurav

Chemical Immunology: Cell specific chemical perturbation of immune microenvironments in cancer, neurological and immunological disorders

Chubykin, Alexander

Neuronal circuits in visual perception and learning Optogenetics Neurotechnology Autism Alzheimer's Disease Stroke

Cui, Meng

Neurophotonics, whole mouse brain high-resolution high-throughput imaging

Culurciello, Eugenio

Biomedical instrumentation

Ekenstedt, Kari

Genetic and genomic investigation of naturally-occurring canine diseases and traits

Fekete, Donna M.

Inner ear development using zebrafish and chicken embryo animal models.

Fox, Edward A.

Sensory component of the vagus nerve; development and role in regulation of food intake and body weight

Francis, Gregory

Neural network models of human behavior, human-computer interactions, cognitive psychology

Freeman, Jennifer L.

Environmental and molecular toxicology, genomics, and cytogenetics

Giordano, Nicholas J.

Nanostructures and mesoscopic systems, musical acoustics, computational neuroscience, computational physics

Heinz, Michael

Neural coding in normal and impaired auditory systems

Hélie, Sebastien

Computational cognitive neuroscience, cognitive psychology, neuroimaging

Hockerman, Gregory

Molecular pharmacology

Hollenbeck, Peter J.

Intracellular organelle transport in neurons

Huber, Jessica E.

Jessica Huber, Ph.D., CCC-SLP, is a Professor in Speech, Language, and Hearing Sciences at Purdue University. The broad aim of her NIH funded research
program is to understand the multiple factors that influence speech production and cognitive change in older adults with and without Parkinson’s disease (PD) and
to translate findings to clinical treatment. Dr. Huber is the inventor of a small wearable device, the SpeechVive device, to treat communication impairments in
people with PD.

Hudmon, Andy

Neuropharmacology, cell signaling, macromolecular machines, ion channels, kinases and calcium signaling.

Kinzer-Ursem, Tamara

Bionanotechnology and biosensors

Kinzig, Kimberly P.

Neural and endocrine factors involved in the control of food intake and regulation of energy balance

Kluender, Keith

Perception of complex sounds, auditory learning

Krishnan, Ananthanarayan

Auditory physiology

Leung, Yuk Fai

Disease-causing gene network and novel therapies for retinal degeneration

Liu, Zhongming

Magnetic resonance imaging, image and signal processing,brain decoding and modeling

Lucas, Jeffrey R.

Use of optimality models in behavioral ecology; energy regulation and communication in birds and mammals

Paschou, Peristera

n/a

Pluta, Scott

Neural basis of sensory perception and sensory-guided behavior

Powley, Terry L.

Identification and mapping of the neural circuitry controlling feeding and drinking

Ramachandran, P. Veeraraghavan

Organic Synthesis and biology of anti-cancer agents and GABA-ergic molecules

Ready, Donald F.

Cellular, molecular, and genetic studies of Drosophila retinal development

Rickus, Jenna L.

NeuroEngineering / Cellular Neurobiology

Robles, Estuardo

The cellular basis of visual processing in zebrafish

Rochet, Jean-Christophe (Chris)

Protein misassembly diseases

Rossie, Sandra S.

Signal transduction and protein Ser/Thr phosphatases

Sangha, Susan

Identification of circuits mediating fear, safety and reward behaviors

Sayles, Mark

Signal processing in auditory brainstem neural circuits Sensory "un-masking" by brainstem circuits Effects of noise-induced hearing loss on neural coding in the central nervous system

Shah, Kavita

Drug Discovery in Cancer and Alzheimer's Disease Using Chemical Biology Tools

Shi, Riyi

Cellular and molecular underlying mechanism of nerve damage and recovery

Sjogren, Benita

Regulator of G protein signaling (RGS) proteins regulation by ubiquitin-proteasomal degradation and post-translational, transcriptional and epigenetic mechanisms. RGS protein drug discovery.

Strickland, Elizabeth A.

Psychoacoustics, auditory perception by normal and hearing impaired listeners

Suter, Daniel M.

Neuronal growth cone motility and guidance, cell adhesion and migration, cytoskeletal dynamics, signal transduction, nervous system development

Swithers, Susan E.

Development of controls of ingestive behavior in rats

Talavage, Thomas

Applications and techniques to enhance clinical usage of functional neuroimaging; cochlear implant signal processing

Tantama, Mathew

Activity-dependent metabolic and oxidative stress in neurons and glia; protein engineering; biosensors; live-cell microscopy; Parkinson’s; glioma; TBI

Rijn, Richard M. Van

G-protein coupled receptor pharmacology of addiction and neurological disorders

Watts, Val J.

Signaling of G protein-coupled receptors with an emphasis on dopamine receptors and adenylate cyclases

Weake, Vikki

Aging photoreceptors in the eye show characteristic changes in gene expression. Our lab is interested in understanding the mechanisms that drive these changes in gene expression. These studies provide a model for understanding how aging contributes to ocular diseases such as age-related macular degeneration. Our work is funded by the National Eye Institute of the NIH. We are actively seeking new graduate students, so please contact us if you are interested in joining our group.

Weber, Christine

Event-related brain potential (ERP) and behavioral measures to characterize the neural subsystems for language processing

Yang, Yang

Specialization: pharmacogenomics, ion channels, electrophysiology, induced pluripotent stem cells (iPSCs), neurological diseases (e.g., chronic pain, epilepsy, and autism)

Zelaznik, Howard N.

Theoretical issues in movement coordination and movement timing

Zheng, Wei

Blood-brain barrier and neurotoxicology of Alzheimer's disease and Parkinsonian disorders