Alex Chubykin

Active Mentor - currently hosting PULSe students for laboratory rotations and recruiting PULSe students into the laboratory; serves on preliminary exam committees

Current Research Interests:

A major challenge in neuroscience is to understand how brain circuits process visual information and how these circuits are altered in Autism Spectrum Disorders (ASDs). To answer these questions, we use a multi-disciplinary approach combining optogenetics, electrophysiology, 2-photon imaging and behavior in genetic models of ASDs.

Selected Publications:

Impaired adaptation and laminar processing of the oddball paradigm in the primary visual cortex of Fmr1 KO mouse A Pak, ST Kissinger, AA Chubykin Frontiers in Cellular Neuroscience 2021

Visual Familiarity Induced 5-Hz Oscillations and Improved Orientation and Direction Selectivities in V1 M Gao, S Lim, AA Chubykin Journal of Neuroscience 41 (12), 2656-2667 2021

Potassium channel-associated bioelectricity of the dermomyotome determines fin patterning in zebrafish MR Silic, Q Wu, BH Kim, G Golling, KH Chen, R Freitas, AA Chubykin, ... Genetics 215 (4), 1067-1084 7 2020

In vivo glutamate sensing inside the mouse brain with perovskite nickelate-nafion heterostructures Y Sun, T Nguyen, A Anderson, X Cheng, TE Gage, J Lim, Z Zhang, ... ACS Applied Materials & Interfaces 2 2020

Three-dimensional nanoscopy of whole cells and tissues with in situ point spread function retrieval F Xu, D Ma, KP MacPherson, S Liu, Y Bu, Y Wang, Y Tang, C Bi, T Kwok, ... Nature methods 17 (5), 531-540 22 2020

Visual experience-dependent oscillations and underlying circuit connectivity changes are impaired in Fmr1 KO mice ST Kissinger, Q Wu, CJ Quinn, AK Anderson, A Pak, AA Chubykin Cell reports 31 (1), 107486 4 2020

Top-down feedback controls the cortical representation of illusory contours in mouse primary visual cortex A Pak, E Ryu, C Li, AA Chubykin Journal of Neuroscience 40 (3), 648-660 9 2020

Cortical tuning is impaired after perceptual experience in primary visual cortex of serotonin transporter-deficient mice A Pak, AA Chubykin Cerebral cortex communications 1 (1), 2020