Deva Chan

Active Mentor - currently hosting PULSe students for laboratory rotations and recruiting PULSe students into the laboratory; serves on preliminary exam committees

Current Research Interests:

Soft tissue biomechanics and extracellular matrix biology, mechanobiology of hyaluronic acid synthesis, and magnetic resonance imaging applied to musculoskeletal and neural biomechanics.

Selected Publications:

Statistical Characterization of Human Brain Deformation During Mild Angular Acceleration Measured In Vivo by Tagged Magnetic Resonance Imaging. Chan DD, Knutsen AK, Lu YC, Yang SH, Magrath E, Wang WT, Bayly PV, Butman JA, Pham DL. J Biomech Eng. 2018 Oct 1; 140. PMID: 30029236.

Functional MRI can detect changes in intratissue strains in a full thickness and critical sized ovine cartilage defect model. Chan DD, Cai L, Butz KD, Nauman EA, Dickerson DA, Jonkers I, Neu CP. J Biomech. 2017 Nov 20. PMID: 29169631.

Pirfenidone reduces subchondral bone loss and fibrosis after murine knee cartilage injury. Chan DD, Li J, Luo W, Predescu DN, Cole BJ, Plaas A. J Orthop Res. 2018 Jan; 36: 365-376. PMID: 28646530.

In vivo articular cartilage deformation: noninvasive quantification of intratissue strain during joint contact in the human knee. Chan DD, Cai L, Butz KD, Trippel SB, Nauman EA, Neu CP. Sci Rep. 2016 6: 19220. PMID: 26752228.

Deficiency of hyaluronan synthase 1 (Has1) results in chronic joint inflammation and widespread intra-articular fibrosis in a murine model of knee joint cartilage damage. Chan DD, Xiao WF, Li J, De La Motte CA, Sandy JD, Plaas A. Osteoarthritis Cartilage. 2015 Nov; 23: 1879-1889. PMID: 26521733.