Claire Pfeffer
Advisor's Name:
Brittany Allen-Petersen
Email Address:
Training Group:
Chromatin Biology and Gene Regulation
Research Summary:
Pancreatic cancer has a 5-year survival rate of just 13%, indicating a critical need for increased understanding of the molecular mechanisms involved in tumorigenesis and progression. My thesis aims to interrogate the complex regulation of critical oncogenic signaling pathways in pancreatic tumors by Protein Phosphatase 2A (PP2A). Results of these studies will define the mechanisms that contribute to pancreatic cancer cell survival and therapeutic resistance, and identify novel roles for PP2A in cancer.
Why did you choose to attend PULSe:
I chose to attend PULSe because of the breadth of research in PULSe and the large number of faculty affiliated with PULSe- it allowed for a lot of flexibility and options.