Yuk Fai Leung

Title:

Associate Professor in Biological Sciences

PhD Granting Institution:

Chinese University of Hong Kong

Contact:

Email Address: yfleung@purdue.edu
Office Phone: 765-496-3153
Lab Website Link: https://leung.bio.purdue.edu/

Primary Training Group:

Integrative Neuroscience

Secondary Training Groups:

Computational and Systems Biology

Research Areas:

Drug discovery for retinal degeneration Retinal degeneration is a group of inherited eye diseases including retinitis pigmentosa and age-related macular degeneration that impair our vision. Although much has been learned about the molecular basis of these diseases, they are still incurable. To expedite discovery of new drugs for these diseases, our group at Purdue University studies zebrafish retinal-degeneration models. We screen drug libraries on these models using high-throughput visual-behaviour assay. We develop novel statistical and machine-learning tools to analyze the large-scale behavioural data, and to to determine which drugs helped the retinal-degeneration models. We then study how the positive drugs work at molecular, genomics and cell-biology levels. Please visit our lab website <https://leung.bio.purdue.edu/> for the most updated information.