Adam Kimbrough
Title:
Assistant Professor
PhD Granting Institution:
Florida State University
Contact:
Email Address: kimbroua@purdue.edu
Office Phone: 64790
Lab Website Link: https://kimbroughlab.com
Primary Training Group:
Integrative Neuroscience
Secondary Training Groups:
Computational and Systems Biology
Research Areas:
Our laboratory is currently interested in understanding how the brain is changed after substance use or neurodegenerative diseases. We are interested in how addiction forms, and alters the brain, leading to motivation for excessive drug intake. Current projects include: 1) determining critical brain regions involved in alcohol drinking, 2) assessing how oxycodone use alters brain structure and function, 3) modeling polysubstance use of alcohol and oxycodone, and 4) determining the potential for alcohol use to increase the risk of neurodegenerative diseases such as Alzheimer's disease.
Current Projects:
We use translationally relevant preclinical animal models of substance use disorder to dissect how the brain responds to acute and chronic drug use. We pair behavioral models with whole-brain imaging of protein signaling and computationally based neural network analysis. These approaches can help us to better understand addiction and develop better treatment options