Shreyas Iyer
Advisor's Name:
Andrea Kasinski
Email Address:
Training Group:
Cancer Biology
Research Summary:
Having previously worked in the RNA therapeutics industry before pursuing graduate school, I recognized the critical barrier to advancing RNAs as cancer therapeutics lies in the absence of suitable delivery mechanisms. Now, during my doctoral training in microRNA delivery under the guidance of Dr. Andrea Kasinski, I'm dedicated to developing a targeted, vehicle-free approach to deliver a chemically modified miR-34a to cancer cells. My focus involves strategies to prolong circulation half-life, improve endosomal escape, and explore combinatorial approaches with standard-of-care therapies for clinical relevance. Ultimately, my goal is to make meaningful contributions that will positively impact the lives of cancer patients.
Why did you choose to attend PULSe:
I chose to attend the PULSe program at Purdue University because of its strong interdisciplinary focus in biology, offering a diverse mix of research labs. The program's structure, which allows rotations in four different labs, provides a unique opportunity to explore various research areas before selecting the best fit for my interests and career goals. This flexibility and exposure to different scientific approaches and techniques were key factors in my decision.