Riyi Shi profile picture

Riyi Shi

Professor of Basic Medical Sciences and Biomedical Engineering

Dr. Shi is a Professor in the Department of Basic Medical Sciences and holds a courtesy appointment in the Weldon School of Biomedical Engineering. Dr. Shi received his MD in Shanghai Jiao-Tong University School of Medicine (China) and his Ph.D. in Neuroscience from Purdue University. He has served as a grant reviewer for numerous federal, state agencies and private foundations, such as NIH, NSF, DOD, American Heart Association, Craig H. Neilsen Foundation for spinal cord injury, the state of New York and the State of Indiana. He is specializing in uncovering the mechanisms of central nervous system trauma and diseases and instituting new treatments through innovative experimentation and pioneering new strategies in the field. His research contributions includes originating the use of double sucrose gap technique for recording action potential conduction, establishing the methods of neuronal membrane resealing by polyethelyne glycol (PEG), identifying acrolein as a key pathological factor in neuronal trauma and degenerative diseases, and establishing novel animal blast injury model. His research interests also include using biomedical engineering principles to enhance neuronal repair and diagnosis. Two of his research has led to the clinical testing treating patients with spinal cord and head trauma, as well as multiple sclerosis. He has published more than 140 peer-reviewed papers and is the recipient of 10 issued patents. His work has been supported by NIH, NSF, DOD, and various private companies, such as MedImmune, Geron, Johnson and Johnson, Amgen and Alfred Mann Institute of Biomedical Development. He has been an invited lecturer over 50 times at national and international events. Dr. Shi’s additional recognitions for research accomplishments include a keynote speech, the 9th European Solid Mechanics Conference, elected as the Founding President, Chinese Neurotrauma Scholar Association (2012-2013, US), named as Outstanding Alumni: Basic Medical Science, Purdue University, and a selection of PVM (Purdue University, College of Veterinary Medicine) Excellence in Research Award. Dr. Shi serves as the chairman of BME/MSTP committee at Purdue. Dr, Shi also served as the founding director for Biomedical Sciences Interdisciplinary Graduate Program. He is also the Director of Deliberate Innovation for Faculty in the medical and Biomedical engineering area at Purdue.