Consultation on assay development, implementation, validation and miniaturization specific to the target of your interest. Type of assays implemented includes:
In vitro enzymatic activity assays
In vitro protein binding assays
Cell proliferation assays
Cell-based transcription (reporter gene)assays
Image-based cell phenotypic screening assays
Pre-plated compound library ready for assays that are performed in 384-(preferred) or 96-well plate format;
High throughput screening and high content screening using liquid handling robots and automated plate readers and high content imaging acquisition and analysis;
Assistance with data analysis and compound selection will be provided as needed;
Post-screen hit validation (dose dependence, binding evaluation, etc.)
Compound management, plating and distribution services
