Hit to Lead Program

In order to advance a hit molecule into a therapeutic lead, many of the compounds attributes must be optimized including solubility, potency, pharmacokinetics, toxicity, etc. These development activities require expertise from a broad interdisciplinary group including biologists, chemists, formulators, and toxicologists to name but a few. A number of core facilities who can help with this type of testing can be found on our affiliated scientific core facilities page.

The Institute for Drug Discovery has assisted faculty in developing their hit molecules into therapeutic leads by providing these funding opportunities: Hit to Lead Program RFA.