Hit to Lead Program

In order to advance a hit molecule into a therapeutic lead, many of the compounds attributes must be optimized including solubility, potency, pharmacokinetics, toxicity, etc. These development activities require expertise from a broad interdisciplinary group including biologists, chemists, formulators, and toxicologists to name but a few. A number of core facilities who can help with this type of testing can be found on our affiliated scientific core facilities page.