Biotechnology
Research includes:
- Bioenergy
- Biofuels
- Bionanotechnology
- Biosensors
- Biospectroscopy and Imaging
- Computational Biology
- Devices
- Engineering
- Human Health
- Instrumentation
- Nanotechnology
- Quantitative Biology
- Renewable Energy
- Systems Biology
- The Environment
Training Group Mission:
The mission of the Biotechnology (BT) Training Group is to develop highly skilled scientists and engineers who excel at the intersection between biology and engineering. The evolution of engineering and its influence on the discovery, design, implementation and translation of biology requires future students who are capable of merging instrumentation, quantitative methods and engineering principles seamlessly into the biology discipline. Because of the breadth in focus, students with both engineering and non-engineering background can be admitted. The training group provides a unique set of courses and lab experiences to provide the quantitative and design background to students interested in exploring the boundaries of science and engineering at Purdue University. The additional expertise required for success in the Biotechnology Training Group requires a minimum of 35 and up to a maximum of 41 credit hours of course-work, which is greater (almost twice) than any other training group and in the range of course-work requirements for engineering departments across campus (eg. ABE: 42, BME: 26). Faculty members of the Training Group have diverse backgrounds and come from diverse departments on campus. Research focus on addressing global challenges related to human health, the environment, biofuels, and renewable energy. The training group provides tremendous opportunities to prepare students for a broad range of career opportunities in industry and academia.
Faculty Membership
1) The role of advanced glycation end-products in the development of diabetic tendinosis 2) The role of estrogen in tendon health 3) Combined
nutrition/exercise approaches to improve tendon properties in older adults.
The Chan Lab believes that understanding the early response to injury is critical to diagnosis, assessment, and intervention in life-altering diseases, including post-traumatic osteoarthritis and traumatic brain injury. True to our biomedical engineering roots, we adopt a multi-disciplinary approach - using biomechanics, biomedical imaging, and matrix biology - to quantify the complex tissue responses to injury.
The research in my lab is geared towards understanding the host-pathogen interaction during migration of zoonotic ascarid larvae of the genera, Toxocara and Baylisascaris within the mammalian host. We use a combination of traditional parasitology, molecular biology and "-omics" related tools for identification and characterization of these parasite proteins. Our goal is to lay down a path to develop efficient diagnostics, identify potential vaccine candidates and drug targets to mitigate the effects of these neglected soil-transmitted nematodes.
Cancer immunotherapy, immunoengineering, natural killer cells, nanomedicine, cell and gene engineering, immunotherapy of solid tumors
Nanomaterials, Environmental and Molecular Toxicology, Nanoparticle-Biomolecule Interactions, Susceptible Subpopulations
Specialization: pharmacogenomics, ion channels, electrophysiology, induced pluripotent stem cells (iPSCs), neurological diseases (e.g., chronic pain, epilepsy, and autism)
