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NIH Competing Renewal R01 Program

Enhancing Purdue’s NIH Research Portfolio

Office of Research
Purdue University
West Lafayette, IN 47907



Standard submission dates are September 22 and February 22 each fall and spring semester.

If due date falls on a weekend, the submission will be accepted through 5:00pm of the following workday.

Funds available

December, May following the fall and spring deadlines

Overview and Purpose

The purpose of the NIH Competing Renewal R01 Program is to increase the submission success rate of NIH R01 renewal applications with the long-term goal of increasing Purdue’s NIH funding portfolio. The backbone of a major research university’s NIH portfolio is R01 awards. A need exists to assist NIH investigators to improve the first submission success rates of R01 competitive renewal applications. A small influx of funds at a pivotal time in the project period will allow freedom to extend studies, try higher risk approaches, or gain access to samples/materials that are beyond the available funds, which are concentrated on the most “doable” experiments. These approaches, if successful, will provide critical data that will increase the probability of success in the renewal process. Examples of experimental approaches that would fall under the Office of Research funding include, but are not limited to: genetically modified experimental animals, global proteomics/metabolomics studies, broad/deep genetic analysis, and advanced imaging studies.


Faculty who hold active NIH R01 grants and anticipate submitting a competitive renewal within 12-18 months of one of the above deadlines are eligible to apply.

Maximum Award

Requests are limited to $50,000 and below.

Application and Submission Process

Applications must use Arial 11 point font with 0.5 inch margins, single line spacing and must follow the supplied NIH Renewal Application Template.

The due dates are based on the NIH competitive renewal funding cycles and are designed to provide funding approximately 12-18 months before the competitive renewal due date. Faculty should work with their pre-award centers to prepare applications, which must be submitted through the pre-award centers to the following InfoReady application page:

Incomplete applications and/or applications that do not meet these requirements will be returned without review.

Allowed Costs

  • It is not the intent of this program to provide salary support for faculty and staff (see FAQs for more information regarding salary support for faculty). Salary support for graduate students is allowed. The major intent of this program is to provide funds for reagents, services, or experimental tools that will enable critical data collection for competitive renewal applications.
  • Equipment purchases are not envisioned as part of this program since they are eligible for funding under the Research Instrumentation Program. However, specialized equipment that would bring significant new capabilities to a project may be considered if carefully justified.

Cost Sharing or Matched Funding

Cost-sharing or matched funding is not allowed.


Recipients must submit a NIH R01 competing renewal application no later than 12-18 months after receiving funding from this program. Failure to do so may result in the recipient becoming ineligible to receive future funding from the Office of Research.

Review Criteria

Proposals will be evaluated on the impact the funding is likely to have on the success of the investigator’s NIH R01 competitive renewal application.

Post-Award and Reporting Requirements

The Principal Investigator must submit to the Office of Research (

  1. an email reporting the date the competitive renewal was submitted
  2. a copy of the review summary of the renewal application when it is received.

Additional Information

Questions may be directed to Perry Kirkham ( or Emily Stevenson (

Frequently Asked Questions

  • Why were specific funding mechanisms (e.g., R01/U01) chosen and not others (e.g., R21)?

    The intent is to target only a few, limited, NIH funding mechanisms of high priority for Purdue. The funding mechanisms chosen were based on the results of a review of the distribution of awards within Purdue’s current NIH funding portfolio and considerations of requirements for preliminary data.

  • Will this be a recurring/annual initiative?

    Our goal is to continue offering the program semiannually.

  • What if my R01 is currently in a No Cost Extension (NCE)?

    If your R01 is currently in a NCE and you have not submitted a competitive renewal, you are eligible for this program. If you have submitted your competitive renewal and you are not successful, then further discussion may be needed. Contact Perry Kirkham ( for further questions.

  • Can a portion of the funds be used to pay faculty salary?

    In general, support for faculty salaries is not the intent of this program. However, individual cases may arise where this is the most productive use of funds. Contact Perry Kirkham ( for further explanation.

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