January 23, 2017
Researchers have discovered a metabolic signature critical for the functioning of "cancer stem cells" that initiate tumor formation. The team also showed how to interfere with this metabolic mechanism in ovarian cancer, inhibiting tumor growth.
Lipid metabolism is potential 'Achilles' heel' for cancer stem cells
January 23, 2017
A research team in the department of Basic Medical Sciences (BMS) has identified a link between the hepatitis B virus (HBV) and the development of liver cancer. Dr. Ourania Andrisani, professor of Basic Medical Sciences, leads the team of graduate research assistants Ahmed Diab, Saravana Kailasam Mani, Dante' Johnson and post-doctoral research associate Zhibin Cui, in collaboration with the research team of professor Philippe Merle from INSERM, France. Using molecular approaches including transfections, fluorescence-activated cell sorting, immunoblotting, and reverse transcription polymerase chain reactions (qRT-PCR), Dr. Andrisani's team investigated the functional significance of epithelial cell adhesion molecule (EpCAM) re-expression in HBV-mediated cancer production in the liver.
