July 11, 2022
During the COVID-19 pandemic, we have seen unprecedented, rapid scientific collaboration, as experts around the world in discrete, previously disconnected fields, have found ways to collaborate to face a common cause. For example, physicists helped respiratory specialists understand how virus particles could spread in air, leading to improved mitigation strategies. Specialists in cardiovascular science, neuroscience, immunology, and other fields are now working together to understand and address Long COVID. Over the past two years, we have also seen remarkable international sharing of epidemiological data and information on effects of vaccines.
Tackling Complex Scientific Questions Requires a Team Approach
July 8, 2022
Immunotherapies, such as immune checkpoint inhibitors, have transformed the treatment of advanced stage cancers. Unlike chemotherapies that kill cancer cells, these drugs help the body's immune system to find and destroy cancer cells themselves. Unfortunately, only a subset of patients responds long-term to immune checkpoint inhibitors -- and these treatments can come at a high cost and with side effects. Researchers have developed a two-step approach using whole exome sequencing to zero in on genes and pathways that predict whether cancer patients will respond to immunotherapy. The study, published in Nature Communications and conducted by researchers at New York University, Weill Cornell Medicine, and the New York Genome Center, illustrates how the use of whole exome sequencing can better predict treatment response than current laboratory tests.
Whole exome sequencing predicts whether patients respond to cancer immunotherapy
July 7, 2022
To give professionals interested in health care an opportunity to develop valuable skills in business, management and quality improvement in health care delivery, Purdue University’s College of Health and Human Sciences is offering two new online graduate certificates in health care operations management and health care quality improvement.
July 7, 2022
Researchers found that high dose nitric oxide given to pregnant women with severe COVID-19 pneumonia resulted in reductions in the need for supplemental oxygen as well as in hospital and ICU lengths of stay, with no adverse events reported in mothers or newborns.
July 7, 2022
Researchers identified significant changes to the infant gut microbiome of mice associated with maternal exposure to oxycodone, a commonly used and abused opioid.
Mouse study links changes in microbiome to prenatal opioid exposure
July 7, 2022
A new study in patients reveals that two newly identified plasma biomarkers of Alzheimer's disease can predict postoperative delirium, one of the most common postoperative complications in older patients. The findings indicate the potential overlap between the mechanisms that cause Alzheimer's disease and postoperative delirium.
Alzheimer's disease biomarkers can predict postoperative delirium
July 7, 2022
Researchers describe a new method to identify all of the unidentified molecules derived from food, providing a direct way to link molecules in diet to health outcomes.
'You are what you eat,' and now researchers know exactly what you're eating
July 7, 2022
Researchers have developed a new tool that could automate the process of diagnosing Alzheimer's disease and eventually allow it to move online.
July 7, 2022
Lung cancer cells harbor significantly more bacteria than other cell types found inside lung tumors, according to new research from CCR scientists. The research team, led by Chen Zhao, M.D., a Physician-Scientist Early Investigator in the Thoracic and GI Malignancies Branch (TGMB), also found that an important tumor-promoting signaling pathway is particularly active in tumor cells with high concentrations of bacteria. Zhao, his mentors Ronald Germain, M.D., Ph.D., National Institute of Allergy and Infectious Disease, and Arun Rajan, M.D., TGMB, along with Zhao’s collaborator Chengcheng Jin, Ph.D., at the University of Pennsylvania, reported their findings July 6, 2022, in the Journal for ImmunoTherapy of Cancer.
July 6, 2022
Older people with hypothyroidism, also called underactive thyroid, may be at increased risk of developing dementia, according to a new study. The risk of developing dementia was even higher for people whose thyroid condition required thyroid hormone replacement medication.
