July 20, 2022
Immature human egg cells skip a fundamental metabolic reaction thought to be essential for generating energy. This helps cells avoid creating reactive oxygen species, harmful molecules that can accumulate, damage DNA and cause cell death. The findings explain how human egg cells remain dormant in ovaries for up to 50 years without losing their reproductive capacity. The findings could lead to new strategies to preserve the ovarian reserves of women undergoing cancer treatment, as well as open new lines of research that explain why one in four cases of infertility are unexplained.
Human eggs remain healthy for decades by putting 'batteries on standby mode'
July 20, 2022
A team has developed a new tool to predict and customize the rate of DNA editing, paving the way for more personalized, efficient genetic and cell therapies for diseases such as diabetes and cancer.
Engineers develop new tool that will allow for more personalized cell therapies
July 20, 2022
Five key methods have been explored by researchers to calculate life expectancy and the life years lost due to disease and illness.
July 20, 2022
A new scale for measuring the psychological safety of patients has been developed.
July 20, 2022
Going to the doctor might make you want to cry, and according to a new study, doctors could someday put those tears to good use. Researchers report a nanomembrane system that harvests and purifies tiny blobs called exosomes from tears, allowing researchers to quickly analyze them for disease biomarkers. Dubbed iTEARS, the platform could enable more efficient and less invasive molecular diagnoses for many diseases and conditions, without relying solely on symptoms.
'iTEARS' could help diagnose diseases by isolating biomarkers in tears
July 20, 2022
Nerve cells regulate and routinely refresh the collection of calcium channels that enable them to send messages across circuit connections.
New findings reveal how neurons build and maintain their capacity to communicate
July 20, 2022
After decades of study, there remains no clear evidence that serotonin levels or serotonin activity are responsible for depression, according to a major review of prior research.
No evidence that depression is caused by low serotonin levels, finds comprehensive review
July 20, 2022
SARS-CoV-2 is covered in spike proteins, which allow the virus to enter host cells once in the body. Researchers have developed a membrane that includes proteolytic enzymes that attach to the protein spikes and deactivate them.
Medical face mask membrane that can capture, deactivate SARS-CoV-2 spike protein on contact
July 20, 2022
Using a GLI inhibitor, rather than a SMO inhibitor, made medulloblastoma tumors smaller and weaker.
July 20, 2022
Studies have shown that physical and mental activity help preserve thinking skills and delay dementia. A new study suggests that these benefits may vary for men and women.
Do benefits of physical, mental activity on thinking differ for men and women?
