September 21, 2022
Key differences in male and female mice brains provide new insights into how sex determines the mechanisms by which distinct synapses monitor and regulate dopamine signaling. The impact of sex differences is particularly pronounced when the mice express a human genetic variant found in boys with either ADHD or autism. Behavioral generalizations across the sexes may limit diagnosis of mental illness, especially if one sex translates alterations into outward signs such as hyperactivity and aggression vs. more internal manifestations such as learning, memory and mood, even when the same molecular pathology is at work.
Rare human gene variant in ADHD, autism exposes fundamental sex differences
September 21, 2022
For men and women, the risk factors for cardiovascular disease are largely the same, an extensive global study shows.
September 20, 2022
Since the early 1990s, federal support of research has increased to understand minority health and identify and address health disparities. Research in these areas has evolved from a starting point of developing a basic descriptive understanding of health disparities and who is most affected. Now, it is discovering the underlying complexity of factors involved in health outcomes to inform interventions and reduce these disparities. One of these many factors is where we live, learn, work, and play and how that affects different people. A group of NIH scientists and their colleagues recently published a study in the journal The Lancet that they hope is a step toward better understanding geographic disparities and their role in health equity.
September 20, 2022
Drinking black tea was associated with a modest reduction in death in a large study. The results support black tea being part of a healthy diet.
September 20, 2022
An advanced computer program was able to identify people with Parkinson’s disease from their breathing patterns during sleep. The program was able to track small changes in the disease over time, and was more accurate than the tools used regularly by doctors.
Night breathing patterns identify people with Parkinson’s disease
September 20, 2022
Cardiovascular disease, which affects the heart and blood vessels, is the nation’s leading cause of death, and Black Americans bear a disproportionate burden. Nearly half of Black adults in this country have cardiovascular disease. Their risk of dying from the condition is 30% higher than the overall U.S. population’s.
Spirituality, religion linked to heart health among Black Americans
September 20, 2022
A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer's disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, according to a new study.
Newly discovered protein connected to Alzheimer's disease risk
September 20, 2022
Deep learning models represent 'an entirely new paradigm for studying dementia.'
September 20, 2022
Aggregates of the protein alpha-synuclein spread in the brains of people with Parkinson's disease through a cellular waste-ejection process, suggests a new study.
Discovery illuminates how Parkinson's disease spreads in the brain
September 20, 2022
Researchers have uncovered a novel pathway that explains how cancer cells become resistant to chemotherapies, which in turn offers a potential solution for preventing chemo-resistance.
Discovery explains cancer chemotherapy resistance, offers solution