September 20, 2022
A topical gel that blocks the receptor for a metabolic byproduct called succinate treats gum disease by suppressing inflammation and changing the makeup of bacteria in the mouth, according to a new study.
September 20, 2022
Scientists explore how digital health solutions can expand audiology services in clinical and research settings. Audiology assessment via telehealth would allow patients to access care while a specialist is located hundreds of miles away and, as a research tool, telehealth would allow for more representative and decentralized data on hearing, without compromising results. The team is currently scaling up several studies they conducted in rural areas of Alaska; their mission is to close the gap on hearing health disparities.
September 20, 2022
Scientists have uncovered a mechanism by which certain breast cancer cells regulate their own metastases, fuel dissemination from the original tumor site, and determine routes to invade distant organs such as the lungs, according to a new study.
September 20, 2022
Scientists have shown that high-fat diets can cause rapid changes in the bone marrow of mice, driving the production of inflammatory immune cells, according to new findings.
High-fat diets trigger inflammatory immune cell generation in bone
September 20, 2022
Study shows women have a higher risk of side effects from immunotherapy, adding to evidence that men and women react differently to treatment.
September 19, 2022
The advent of small-molecule targeted therapies, a decade ago, revolutionized the treatment of metastatic melanoma, provided that the tumors carry the mutations to respond to these treatments. However, despite a remarkable initial response that can be seen in a majority of patients, most of them will undergo relapse even after spectacular initial responses. These relapses are due to 'dormant' persistent cells, unresponsive to treatment.
September 19, 2022
A person's distrust in humans predicts they will have more trust in artificial intelligence's ability to moderate content online, according to a recently published study. The findings, the researchers say, have practical implications for both designers and users of AI tools in social media.
People who distrust fellow humans show greater trust in artificial intelligence
September 19, 2022
In lab experiments, researchers observed a molecule called EGCG break up tau tangles extracted from Alzheimer's disease brain tissue EGCG does not, however, easily penetrate the human brain. They found two other molecules -- CNS-11 and CNS-17 -- that work like EGCG to stop tangles spreading cell to cell but are better leads for drugs.
Newly identified small molecules break amyloid tangles that cause Alzheimer's
September 15, 2022
Recruitment has begun for a clinical study that investigators hope will move “liquid biopsy” technology closer to its still-distant goal: a single blood test for the early detection of cancer. Collectively known as multi-cancer early detection (MCED) assays or sometimes multi-cancer detection assays (MCD), this new advancing technology is a promising concept for cancer screening, but there are key unanswered questions.
September 15, 2022
The overall goal of cancer screening is to reduce suffering from cancer and save lives by identifying precancer or cancer before it causes symptoms. For example, colorectal cancer screening substantially reduces the risk of developing and dying from colorectal cancer and screening mammography can reduce deaths from breast cancer. Although these screening tests and other methods successfully detect precancers and early cancers in people without symptoms, the tests are limited to only a few common cancer types. For many cancers, there are no effective screening tools. Symptoms of deadly late-stage disease for these unscreened cancers may be the first sign that something is wrong. Asymptomatic multi-cancer detection (MCD) tests have the potential to substantially change this narrative. Using a single blood draw, these tests may be able to detect the presence of multiple cancer types—including ones without established screening methods.
Asymptomatic Multi-Cancer Detection: Advancing Cancer Screening to Save Lives
