Past News

Novel PET imaging agent detects earliest signs of Alzheimer's disease

October 19, 2022

A new highly selective PET imaging agent can detect the presence of overexpressed monoamine oxidase-B (MAO-B) in cognitively unimpaired individuals with high beta amyloid -one of the earliest signs of Alzheimer's diseas-according to new research. The radiotracer, 18F-SMBT-1, allows for a better understanding of the role of inflammation in Alzheimer's disease, which can enable more accurate staging and prognosis at earlier stages.

Novel PET imaging agent detects earliest signs of Alzheimer's disease

Corrupt endothelial cells protect blood cancer cells from chemotherapy

October 19, 2022

Endothelial cells -- the cells that line blood vessels -- grown alongside leukemia cells become corrupted and rescue the cancer cells from many chemotherapy drugs, a study found.

Corrupt endothelial cells protect blood cancer cells from chemotherapy

Can obesity and stress influence appetite? New study shows it's all in your head

October 19, 2022

In a series of experiments using functional magnetic resonance imaging (fMRI) to measure brain activity across networks in the brain, researchers looked at how stress might increase appetite in obese and lean adults.

Can obesity and stress influence appetite? New study shows it's all in your head

Environmental chemicals increase risk of inflammatory bowel disease

October 19, 2022

A new study leverages multiple research platforms to systematically identify environmental chemical agents that influence gastrointestinal inflammation.

Environmental chemicals increase risk of inflammatory bowel disease

Beauty products with fluorinated ingredients may also contain PFAS, study reports

October 19, 2022

Smooth, foamy, water-proof. These characteristics are extremely desirable in beauty products, but manufacturers sometimes use ingredients that contain fluorine -- including potentially harmful per- and polyfluoroalkyl substances (PFAS) -- to achieve them. Now, researchers show that some cosmetics and personal care products labeled as having fluorinated components also contain PFAS, whether or not these 'forever chemicals' were listed as ingredients.

Beauty products with fluorinated ingredients may also contain PFAS, study reports

Sleep as a new 8th measure of cardiovascular health

October 19, 2022

Researchers have evaluated an expanded measure of cardiovascular health (CVH) that includes sleep as an eighth metric, in relation to cardiovascular disease risk.

Sleep as a new 8th measure of cardiovascular health

Microbial origins of Type 1 diabetes

October 19, 2022

A bacterial protein called BefA disrupts cell membranes -- and this disruption makes vital insulin-producing cells in the pancreas reproduce early in development. The finding points to a possible way to bolster this cell population, protecting against Type 1 diabetes.

Microbial origins of Type 1 diabetes

Indiana CTSI pilot funding leads to five-year grant for a “Drug-Free Communities” program in Clinton County

October 18, 2022

Vicki Simpson, PhD, associate professor of nursing at Purdue University, in collaboration with Lorra Archibald, executive director of the Healthy Communities of Clinton County Coalition, were recently awarded a five-year grant totaling $625,0000 to prevent and reduce youth substance abuse in Clinton County. The multi-year Drug-Free Communities (DFC) Support Program grant comes after building an eight-year relationship with the Healthy Communities of Clinton County Coalition, which has implemented multiple programs supporting the health and wellness of residents through Indiana Clinical and Translational Sciences Institute (CTSI) Community Health Partnerships (CHeP) Trailblazer awards and a CHeP planning grant award.

Indiana CTSI pilot funding leads to five-year grant for a “Drug-Free Communities” program in Clinton County

Bionic pancreas simplifies management of type 1 diabetes

October 18, 2022

A bionic pancreas managed blood glucose levels in people with type 1 diabetes better and with less user input than existing methods. Such a device could make managing blood glucose easier and improve quality of life for people with type 1 diabetes.

Bionic pancreas simplifies management of type 1 diabetes

The unique way this virus sneaks into a cell's nucleus could advance the study of cancer-causing pathogens

October 18, 2022

A study takes a closer look at a virus that causes tumors in monkeys called SV40. The unique way it infects a cell's nucleus could underpin its ability to cause cancer.

The unique way this virus sneaks into a cell's nucleus could advance the study of cancer-causing pathogens