November 7, 2022
Cervical cancer killed 342,000 women around the world in 2020. According to the World Health Organization, the vast majority of these women — about 90% — lived in low- and middle-income countries where access to testing for early detection is either unaffordable or nonexistent. Purdue researchers Jacqueline Linnes and Sulma Mohammed are determined to save lives by developing a low-cost, point-of-care paper test that could revolutionize cervical cancer detection worldwide.
WGHI Research News: Affordable cervical cancer test holds life-preserving promise
November 2, 2022
Researchers have developed a three-dimensional model that shows how exposure to cadmium might lead to congenital heart disease. Affecting nearly 40,000 newborns a year, congenital heart disease is the most common type of birth defect in the United States. The model was created by scientists at the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health.
New 3D model shows how cadmium exposure may affect heart development
November 2, 2022
Taking a personalized approach to kidney disease screening for people with type 1 diabetes (T1D) may reduce the time that chronic kidney disease (CKD) goes undetected, according to a new analysis performed by the Epidemiology of Diabetes Interventions and Complications study group, which is funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health. The finding, published in Diabetes Care(link is external), provides the basis for the first evidence-based kidney screening model for people with T1D.
NIH-funded study finds personalized kidney screening for people with type 1 diabetes could reduce costs, detect disease earlier
November 2, 2022
A new therapy developed by Purdue researchers may help to address a disease that causes pain in leg or hip muscles while walking, eroding mobility for an estimated 236 million people worldwide. The disease often goes untreated, but, in a clinical trial, researchers are hoping that leg heat therapy, delivered at home using hot-water-circulating pants, may improve walking tolerance in people with lower-extremity peripheral artery disease (PAD).
Purdue News:Leg heat therapy offers simple remedy for disease that causes pain while walking
November 1, 2022
A study in mice found that eating burns more energy when restricted to certain times of the day. The findings explain one reason why the timing of eating can affect weight gain.
October 25, 2022
Researchers found how an enzyme called USP11 contributes to the buildup of tau tangles in the brain, a hallmark of Alzheimer’s disease. In mice, blocking this enzyme protected against loss of memory and learning. USP11 is far more abundant in women than men, and the results suggest it plays a role in the higher risk of Alzheimer’s among women.
Potential contributor to sex differences in Alzheimer’s risk
October 20, 2022
A major clinical trial looking at surgery for women at risk of miscarriage and stillbirth have found that a type of wire commonly used reduces risk of infection.
Single stranded suture threads could prevent pregnancy infection complications, C-STICH trial finds
October 20, 2022
At population level, passive monitoring of walking activity using smartphones offers a pathway toward national screening for health and mortality risk, researchers conclude.
October 20, 2022
Scientists have found that a stress response in cells, when 'switched on' at a post-reproductive age, could be the key to slow down ageing and promote longevity.
Manipulating stress response in cells could help slow down aging
October 19, 2022
Black adults treated at advanced heart failure centers received potentially life-changing therapies, such as transplants and heart pumps, about half as often as white adults, possibly due to racial bias, a small National Institutes of Health-supported study has found. Researchers followed 377 patients receiving treatment at one of 21 centers in the United States and found that 62 of 277 white adults (22%) received a heart transplant or ventricular assist device (VAD), a mechanical device that pumps blood for the heart. In comparison, 11 of 100 Black adults (11%) received these end-stage heart failure therapies, which can extend and improve a patient’s quality of life.
NIH-supported study finds racial disparities in advanced heart failure treatment
