February 1, 2021
In this review, we summarize the role of obesity in carcinogenesis, providing details on specific cancer sites. Special emphasis is given to gender differences in obesity-related cancers and on the effect of bariatric surgery on cancer risk.
February 1, 2021
Religious and spiritual practices, including Kirtan Kriya, are crucial components in the development of enhanced cognition and well-being, which may help prevent and, in some cases, reverse cognitive decline. The key point of this review is that making a commitment to live a brain longevity lifestyle including spiritual fitness is critically important way for aging Alzheimer's disease free. We hope that this article will inspire scientists, clinicians, and patients to embrace this new concept of spiritual fitness and make it part of every multidomain program for the prevention of cognitive disability.
Spiritual Fitness: A New Dimension in Alzheimer's Disease Prevention
January 31, 2021
The rapid spread of the COVID-19 pandemic and subsequent countermeasures, such as school closures, the shift to working from home, and social distancing are disrupting economic activity around the world. As with other major economic shocks, there are winners and losers, leading to increased inequality across certain groups. In this project, we investigate the effects of COVID-19 disruptions on the gender gap in academia. We administer a global survey to a broad range of academics across various disciplines to collect nuanced data on the respondents’ circumstances, such as a spouse’s employment, the number and ages of children, and time use. We find that female academics, particularly those who have children, report a disproportionate reduction in time dedicated to research relative to what comparable men and women without children experience. Both men and women report substantial increases in childcare and housework burdens, but women experienced significantly larger increases than men did.
COVID-19 Disruptions Disproportionately Affect Female Academics
January 29, 2021
The World Health Organization on Friday changed its advice for pregnant women considering a Covid-19 vaccine, abandoning language opposing immunization for most expectant mothers unless they were at high risk. The new wording followed an outcry to the W.H.O.’s guidance for pregnant women. It still “recommends not to use” the vaccines for pregnant women unless the women are at high risk because of potential exposures or underlying health conditions.
Pregnant Women May Receive Covid Vaccines Safely, W.H.O. Says
January 28, 2021
regnant women who experienced severe symptoms of COVID-19 had a higher risk of complications during and after pregnancy, according to preliminary findings from a National Institutes of Health study. Compared to COVID-19 patients without symptoms, those with severe symptoms were at higher risk for cesarean delivery, postpartum hemorrhage, hypertensive disorders of pregnancy and preterm birth.
Severe COVID-19 in pregnancy associated with preterm birth, other complications
January 28, 2021
Do you need some guidance on preparing a K Award application for the NIH? Dr. Kay Lund, Director of Division of Biomedical Research Workforce, gives some great tips in a 25-minute YouTube video, “Writing an Effective ‘K’ Application,” originally presented at the Fall 2020 NIH Virtual Seminar on Program Funding and Grants Administration.
January 28, 2021
With new algorithms, wearable devices—collecting vital signs like heart rate and skin temperature—could catch illness early
January 27, 2021
Wearable devices already collect vital signs like heart rate and skin temperature. New algorithms can use them to catch illness early — leading to urgent efforts to help battle the pandemic.
January 27, 2021
Certain inherited mutations increase an individual’s risk of developing small cell lung cancer, an aggressive form of lung cancer, according to a new study from CCR scientists. However, patients with the disease who harbor these mutations may be more likely than others to respond to therapies that exploit defects in DNA repair pathways; they also appear to have a better prognosis when treated with a standard chemotherapy regimen. The findings, reported January 27, 2021, in Science Translational Medicine, could help clinicians identify the best individualized treatments for the disease.
Genetics, not just smoking, influence small cell lung cancer risk
January 27, 2021
Cancer is the second leading cause of death worldwide, with 9.6 million people estimated to have died of cancer in 2018. Excess body fat deposition is a risk factor for many types of cancer. Men and women exhibit differences in body fat distribution and energy homeostasis regulation. This systematic review aimed to understand why sex disparities in obesity are associated with sex differences in the incidence of gastrointestinal cancers. Cancers of the esophagus, liver, and colon are representative gastrointestinal cancers, and obesity is a convincing risk factor for their development. Numerous epidemiological studies have found sex differences in the incidence of esophageal, liver, and colorectal cancers. We suggest that these sexual disparities are partly explained by the availability of estrogens and other genetic factors regulating inflammation, cell growth, and apoptosis. Sex differences in gut microbiota composition may contribute to differences in the incidence and phenotype of colorectal cancer. To establish successful practices in personalized nutrition and medicine, one should be aware of the sex differences in the pathophysiology and associated mechanisms of cancer development.
Sex Differences in the Incidence of Obesity-Related Gastrointestinal Cancer
