February 17, 2022
Girls with autism differ in several brain centers compared with boys with autism, suggesting gender-specific diagnostics are needed, a new study using artificial intelligence finds.
Study shows differences between brains of girls, boys with autism
February 17, 2022
Fat tissue plays an important role in human health. However, our fat tissue loses function as we age, which can lead to type 2 diabetes, obesity, cancer and other ailments. High levels of lifelong exercise seem to counteract this deterioration.
Well-functioning fat may be the key to fewer old-age ailments
February 17, 2022
Epidemiological data have long linked depression with Alzheimer’s disease (AD), a neurodegenerative disease characterized by progressive dementia that affects nearly 6 million Americans. Now, a new study identifies common genetic factors in both depression and AD. Importantly, the researchers found that depression played a causal role in AD development, and those with worse depression experienced a faster decline in memory.
February 16, 2022
NIH recently published a full report on its fiscal years (FY) 2019 and 2020 research activities pertaining to the health of women. The Report of the Advisory Committee on Research on Women’s Health: Office of Research on Women's Health and NIH Support for Research on Women's Health, known as the biennial report, details the NIH-wide programs and accomplishments carried out in fulfillment of ORWH’s core mission. It also includes a summary of ORWH activities during FY 2019–2020.
Report of the Advisory Committee on Research on Women’s Health: Fiscal Years 2019–2020
February 16, 2022
To enhance the regeneration of bone, the Food and Drug Administration (FDA) approved recombinant human bone morphogenetic protein-2, or BMP-2. However, it is expensive and only moderately effective. It also produces side effects -- some severe. Researchers may have a viable, less risky alternative: messenger RNA. This well-known platform for vaccines has already proven to be safe in human use by the FDA.
February 16, 2022
Researchers have shown that commensal microbes in the mouth, in contrast to commensal microbes colonizing other body surfaces, e.g., the gut or skin, modulate immune responses in the jaw bone that promote bone-resorbing osteoclasts and bone loss. In a preclinical model, depleting healthy commensal microbes in the mouth, using an antiseptic oral rinse, was shown to protect against this bone loss.
February 16, 2022
Researchers have developed a novel method of measuring growth in the aorta that may help clinicians to identify potentially fatal heart conditions earlier. The technique, called vascular deformation mapping, measures changes in the thoracic aorta by using high-resolution CT imaging to calculate three-dimensional changes in the aortic wall. In the study, VDM significantly outperformed the standard manual rating methods performed by experts.
A new tool for 3-D measurement of the aorta may identify fatal heart conditions earlier
February 15, 2022
A combined analysis of results from 149 earlier studies finds that treatment rates for major depressive disorder remain low worldwide, particularly for people living in low and lower-middle income countries.
Study highlights worldwide disparities in treatment rates for major depressive disorder
February 15, 2022
New studies emerge daily on the effect of the human microbiome on human health: colon cancer, ulcers, and cognitive conditions such as Alzheimer's disease have been associated with the communities of microbes that live in our bodies. However, global research into the human microbiome is heavily biased in favor of wealthy countries such as the United States and United Kingdom, according to a new study.
Human microbiome research excludes developing world, study finds
February 15, 2022
The impact of the COVID-19 pandemic hit hardest in deprived areas of England and Wales, with excess years of life lost more than three times as high in the North West than the South West of England. The research also finds 11 times as many excess deaths in 15-44 year olds in the most deprived areas compared to the most affluent ones.
Years of life lost during the pandemic significantly higher in deprived areas, study finds
