September 12, 2023
The Animal Disease Diagnostic Laboratory opened as an official stand-alone facility in 1947 on Purdue University’s West Lafayette, Indiana campus, but its origin actually dates back to 1912 when its initial operations began as a testing laboratory for vaccines to prevent and control hog cholera. As such, the laboratory was one of the first resources in the United States dedicated exclusively to the diagnosis of animal diseases. The ADDL and the Heeke Laboratory focus on helping Indiana veterinarians, animal health officials, livestock producers and animal owners protect the health of the animal population by providing prompt, accurate and reliable diagnoses of animal diseases, including those that may also affect the human population.
Purdue ADDL joins the Swine Disease Reporting System network
September 11, 2023
A Purdue University research group led by biochemistry professor W. Andy Tao collaborated with Tymora Analytical Operations, The Michael J. Fox Foundation for Parkinson's Research and Columbia University for a study that found a non-invasive way to potentially detect Parkinson’s disease in a patient’s urine.
Purdue research: Liquid biopsy method may reveal signs of Parkinson’s disease in urine samples
September 11, 2023
Amplified Sciences, which is developing a platform to diagnose pancreatic cancer earlier among high-risk patients, recently completed a $1.5 million wave of funding that is part of an open Series Seed Preferred round, and that number could more than double.
September 8, 2023
David Cappelleri, professor of mechanical engineering and biomedical engineering (by courtesy), came up with the idea for the world’s smallest drum to test out the Nanoscribe Photonic Professional GT2 3D printer, which streamlines the production of microscopic materials while pioneering new potential applications in medical treatments. Housed at Birck Nanotechnology Center in Discovery Park District at Purdue, the printer is the first of its kind in operation in Indiana and was acquired with a financial award from the U.S. National Science Foundation.
New 3D printing technology is expanding horizons for microrobotics research on Purdue’s campus
September 7, 2023
Scientists already know that traumatic brain injury (TBI) increases the risk of developing Alzheimer's disease, but it's not clear why. A new study has shed some light on this, and on how factors behind Alzheimer's risk emerge almost immediately after a concussion. A team led by Purdue University has developed what they're calling a 'mini-brain', which houses clusters of cultured mouse neurons alongside nutrients in a tiny chamber. This device can then be used to examine the effects of heavy impacts on brain cells. "We're basically creating a miniature brain that we can hit and then study," says neuroscientist Riyi Shi, from Purdue University.
Damage Responsible For Alzheimer's Can Appear Within Hours of a Blow to The Head
September 7, 2023
What occurs after a concussion, and why may it have a connection to Alzheimer’s disease, is the topic of some ground-breaking new study that hopes to shed fresh light on an old cause-and-effect relationship. Old data has demonstrated that traumatic brain injury (TBI), often known as a concussion, makes a person more likely to acquire Alzheimer’s disease; nevertheless, up until now, that was all we knew. Now, new research has thrown some light on this topic, as well as how the elements that contribute to an increased risk of Alzheimer’s disease begin to manifest themselves practically right away following a concussion.
Alzheimer’s Could Install Quickly After a Concussion; New Data Found
September 6, 2023
Scientists in Indiana have been investigating the link between traumatic brain injuries and Alzheimer's by using a 'mini-brain' chip to simulate when a person is hit on the head.
Scientists investigating clear link between dementia and common brain injury
September 6, 2023
Alois Alzheimer reported lipid-filled glia surrounding amyloid plaques in the AD brain. But how and why they appear remains elusive. Now, two bioRxiv preprints blame A?. In one, posted June 6, scientists led by Gaurav Chopra of Purdue University, West Lafayette, Indiana, and Dimitrios Davalos at Ohio’s Cleveland Clinic reported that mouse microglia shift their lipid metabolism when exposed to A? fibrils in vitro.
September 6, 2023
Traditional biopsies use needles to extract cells or tissues for testing. Painful and invasive, they are best known for their use in cancer diagnostics. And though useful for initial diagnosis, needle biopsies present significant health risks so physicians cannot use them to look at tumor heterogeneity, metastasis or behavior over time. To take the sting out of biopsies and address their limitations, scientists have developed a new diagnostic and monitoring tool: the liquid biopsy. Instead of a needle painfully invading patient tissues, a liquid biopsy uses a small amount of blood, saliva or urine to test for disease-related materials such as DNA or proteins, sometimes called biomarkers, in the affected organ. With these biomarkers, physicians can easily determine the presence and severity of a disease.
September 5, 2023
With a custom-fabricated experimental chamber housing a “mini brain,” Riyi Shi traces the link between concussion and Alzheimer’s disease.
A 'mini-brain' traces the link between concussion and Alzheimer’s diseas
