September 8, 2023
David Cappelleri, professor of mechanical engineering and biomedical engineering (by courtesy), came up with the idea for the world’s smallest drum to test out the Nanoscribe Photonic Professional GT2 3D printer, which streamlines the production of microscopic materials while pioneering new potential applications in medical treatments. Housed at Birck Nanotechnology Center in Discovery Park District at Purdue, the printer is the first of its kind in operation in Indiana and was acquired with a financial award from the U.S. National Science Foundation.
New 3D printing technology is expanding horizons for microrobotics research on Purdue’s campus
September 7, 2023
Scientists already know that traumatic brain injury (TBI) increases the risk of developing Alzheimer's disease, but it's not clear why. A new study has shed some light on this, and on how factors behind Alzheimer's risk emerge almost immediately after a concussion. A team led by Purdue University has developed what they're calling a 'mini-brain', which houses clusters of cultured mouse neurons alongside nutrients in a tiny chamber. This device can then be used to examine the effects of heavy impacts on brain cells. "We're basically creating a miniature brain that we can hit and then study," says neuroscientist Riyi Shi, from Purdue University.
Damage Responsible For Alzheimer's Can Appear Within Hours of a Blow to The Head
September 7, 2023
What occurs after a concussion, and why may it have a connection to Alzheimer’s disease, is the topic of some ground-breaking new study that hopes to shed fresh light on an old cause-and-effect relationship. Old data has demonstrated that traumatic brain injury (TBI), often known as a concussion, makes a person more likely to acquire Alzheimer’s disease; nevertheless, up until now, that was all we knew. Now, new research has thrown some light on this topic, as well as how the elements that contribute to an increased risk of Alzheimer’s disease begin to manifest themselves practically right away following a concussion.
Alzheimer’s Could Install Quickly After a Concussion; New Data Found
September 6, 2023
Scientists in Indiana have been investigating the link between traumatic brain injuries and Alzheimer's by using a 'mini-brain' chip to simulate when a person is hit on the head.
Scientists investigating clear link between dementia and common brain injury
September 6, 2023
Alois Alzheimer reported lipid-filled glia surrounding amyloid plaques in the AD brain. But how and why they appear remains elusive. Now, two bioRxiv preprints blame A?. In one, posted June 6, scientists led by Gaurav Chopra of Purdue University, West Lafayette, Indiana, and Dimitrios Davalos at Ohio’s Cleveland Clinic reported that mouse microglia shift their lipid metabolism when exposed to A? fibrils in vitro.
September 6, 2023
Traditional biopsies use needles to extract cells or tissues for testing. Painful and invasive, they are best known for their use in cancer diagnostics. And though useful for initial diagnosis, needle biopsies present significant health risks so physicians cannot use them to look at tumor heterogeneity, metastasis or behavior over time. To take the sting out of biopsies and address their limitations, scientists have developed a new diagnostic and monitoring tool: the liquid biopsy. Instead of a needle painfully invading patient tissues, a liquid biopsy uses a small amount of blood, saliva or urine to test for disease-related materials such as DNA or proteins, sometimes called biomarkers, in the affected organ. With these biomarkers, physicians can easily determine the presence and severity of a disease.
September 5, 2023
With a custom-fabricated experimental chamber housing a “mini brain,” Riyi Shi traces the link between concussion and Alzheimer’s disease.
A 'mini-brain' traces the link between concussion and Alzheimer’s diseas
September 1, 2023
Purdue Research Spearheaded by Dr. Riyi Shi Could Help Lead to Proper Treatments Against Long-term Effects Soon After Head Trauma
PVM Scholar Utilizes ‘Mini-brain’ to Trace Link between Concussion and Alzheimer’s Disease
August 31, 2023
By controlling the arrangement of multiple inorganic and organic layers within crystals using a novel technique, researchers at Duke University and Purdue University have shown they can control the energy levels of electrons and holes (positive charge carriers) within a class of materials called perovskites. This tuning influences the materials' optoelectronic properties and their ability to emit light of specific energies, demonstrated by their ability to function as a source of lasers.
August 31, 2023
Clinton Veale and Fanie van Heerden discuss the story of natamycin. From its humble telluric origins in Pietermaritzburg, this unique antimicrobial agent has risen to become a mainstay of the food and beverages industry.
