November 16, 2023
College of Pharmacy researchers develop small-molecule degrader to target enzyme that plays a role in tumor cells and the immune system.
Purdue pharmaceutical compound sounds the alarm on cancer cells and unleashes T cells
November 16, 2023
Researchers at Purdue University have discovered a compound they say could revolutionize cancer treatment. Professor Zhong-Yin Zhang says it took two years of hard work to synthesize the compound known as TP1L. Put simply, he says the compound fights cancerous cells in the body from the inside and not the outside.
November 16, 2023
Understanding the biological functions of proteins is of fundamental importance in modern biology. To represent function of proteins, Gene Ontology (GO), a controlled vocabulary, is frequently used, because it is easy to handle by computer programs avoiding open-ended text interpretation. Particularly, the majority of current protein function prediction methods rely on GO terms. However, the extensive list of GO terms that describe a protein function can pose challenges for biologists when it comes to interpretation.
GO2Sum: Generating Human Readable Functional Summary of Proteins from GO Terms
November 16, 2023
Researchers at Purdue University just announced a breakthrough that could revolutionize cancer treatment. It took two years of hard work to synthesize the compound known as TP1L. “It’s really a dream come true,” said Purdue professor Zhong-Yin Zhang, who led a team of researchers who discovered the new compound. The compound is different from other immunotherapies that have been developed to fight cancer because it works on the inside of the cells and not the outside.
November 16, 2023
Researchers at Purdue University have made a remarkable breakthrough in cancer treatment that has the potential to revolutionize the field. After two years of dedicated work, they have successfully synthesized a compound called TP1L, which could pave the way for innovative approaches in cancer therapy. Leading the team of researchers, Purdue professor Zhong-Yin Zhang expressed his excitement, stating that the development of TP1L is truly a dream come true. What sets this compound apart from other immunotherapies is its unique ability to target the internal workings of cancer cells rather than external factors. By stimulating the body’s own immune system, TP1L activates its natural ability to recognize and fight cancer cells. The compound aims to counteract the suppression of anti-cancer immunity that occurs within tumor micro-environments. As Zhang explains, it’s as if the tumor is wearing an invisibility cloak, but TP1L can swiftly remove that barrier and unleash the immune system’s full potential to attack tumors head-on.
Scientists at Purdue University Announce Groundbreaking Discovery in Cancer Treatment Research
November 15, 2023
Measuring the strength of concrete in highways and bridges has traditionally entailed “heavy equipment, extensive labor, and considerable uncertainty,” says Luna Lu, an associate dean and engineering professor at Purdue University who started Wavelogix, the company that makes Rebel Concrete Strength Sensors. The sensors, which are installed on a stretch of road before concrete is actually poured, transmit real-time data about the material directly to engineers’ smartphones, allowing them to ascertain when new construction is strong enough to handle cars or when to shut down a highway for repairs.
Wavelogix Rebel Concrete Strength Sensors: The 200 Best Inventions of 2023.
November 13, 2023
The American Cancer Society (ACS), the largest non-government, non-profit funding source of cancer research in the United States, has approved funding for 131 new Extramural Discovery Science (EDS) research and career development grants totaling $64.5 million. The grants will fund investigators at 72 institutions across the United States starting in 2024.
American Cancer Society Awards 131 New Research and Career Development Grants Totaling $64.5 Million
November 10, 2023
Two JKUAT students from the Schools of Medicine and Biomedical Sciences have been awarded opportunities for medical electives and masters programs in Biomedical Engineering at Purdue University.
November 10, 2023
Spraying a stretchy and conductive polymer onto any store-bought garment turns it into a sensor for monitoring body movement during physical therapy.
Spray-on sensors can turn any clothing into motion-sensing technology
November 9, 2023
Dr. Allen Templeton of Merck & Co. and Dr. Stephen Byrn of Purdue University initiated a scientific project that proposed using synchrotron X-ray pair distribution function (SXPDF) and solid-state nuclear magnetic resonance (ssNMR) techniques to investigate amorphous pharmaceutical solids. Since then, scientists from Merck, Purdue, Argonne National Laboratory, and Improved Pharma have been collaborating on a research project involving the structure of amorphous posaconazole (POSA) and amorphous solid dispersions (ASDs) with hydroxypropyl methylcellulose acetate succinate (HPMCAS-L). Their work is described in the latest issue of Molecular Pharmaceutics.
Joint research collaboration between Merck, Purdue University, Argonne National Laboratory, and Improved Pharma
