February 29, 2024
A Dual Approach to a Complex Disorder - The strategy, detailed in a recent announcement from Purdue University, leverages the unexpected potential of rapamycin and statins—drugs initially approved for entirely different purposes. Rapamycin, known as an anti-tumor drug and for its role in preventing organ rejection, and statins, commonly associated with cholesterol management, have shown promising results in reversing symptoms of Lowe syndrome. This innovative approach targets specific biochemical pathways implicated in the disorder, with early tests revealing patient cells beginning to behave as normal.
Pioneering Hope: Purdue University's Breakthrough in Lowe Syndrome Treatmen
February 28, 2024
Purdue University researchers have developed a patented therapeutic strategy for Lowe syndrome, an incurable and rare genetic disorder, by repurposing two drugs previously approved by the U.S. Food and Drug Administration for other conditions. R. Claudio Aguilar created the treatment method, which has the potential to reverse the symptoms of Lowe syndrome and offer patients a higher quality of life. Aguilar is a professor of biological sciences in Purdue’s College of Science, a Showalter Faculty Scholar, and a faculty member of the Purdue Institute for Cancer Research and the Purdue Institute for Drug Discovery.
Purdue researchers test previously approved FDA drugs to treat Lowe syndrome
February 26, 2024
Although the US Preventive Services Task Force recommends universal hepatitis C virus (HCV) screening for all individuals 18-79 years of age, findings from a recent study suggest providers may still be basing their recommendations on patient risk factors and overlooking screening in patients perceived to be at average-risk of infection.
Providers May Be Overlooking Average-Risk Patients for HCV Screening
February 22, 2024
The Midwest Microbiome Symposium is making its return to Purdue University’s Beck Agricultural Center May 13-15. Originated and hosted by Purdue Applied Microbiome Sciences (PAMS), this three-day seminar will unravel the latest developments in the field of microbiome research.
Purdue Applied Microbiome Sciences to host 2024 Midwest Microbiome Symposium
February 22, 2024
The gut microbiome interacts with the loss of female sex hormones to exacerbate metabolic disease, including weight gain, fat in the liver and the expression of genes linked with inflammation, researchers found in a new rodent study.
Mice study suggests metabolic diseases may be driven by gut microbiome, loss of ovarian hormones
February 21, 2024
In a groundbreaking revelation, researchers at Purdue University have shattered conventional norms by harnessing an unexpected ally in the battle against chemoresistance: Doppler ultrasound.
February 20, 2024
Purdue University’s Department of Biological Sciences recently held the inaugural lecture of the new William A. and Hanni Aebersold Cramer Lectures in Biophysics Series. Funded by William Cramer, the emeritus Henry Koffler Distinguished Professor of Biological Sciences, and his wife, the lecture series was established as a testament to the couple’s commitment to advance molecular biophysics research and education at Purdue. Their donation will support the annual lecture series for more than 10 years.
Inaugural Cramer lecture: A new chapter in molecular biophysics at Purdue University
February 9, 2024
Researchers at Purdue University have developed a technique to better predict chemotherapy resistance in canines and humans.
Purdue Researchers Edge Closer to Delivering Personalized Medicine to Cancer Patients
February 7, 2024
Purdue University’s College of Engineering online master’s degrees and College of Education offerings again ranked among the nation’s elite in the newest U.S. News & World Report rankings of best online programs. Purdue online master’s degrees in industrial engineering, mechanical engineering and engineering management all ranked No. 1 for 2024 — the fifth consecutive year industrial and mechanical engineering have topped the list, and the third year for engineering management.
Purdue University Online continues to achieve high national rankings
February 5, 2024
The advance of genetic function indicators has enabled the observation of neuronal activities at single-cell resolutions.
