Research Foundation News

August 14, 2019

The power of 4D technology advances care for heart patients


Ultrasound techniques offer new options, advanced images for doctors, patients

WEST LAFAYETTE, Ind. – A tool that has been around for decades shows new promise in helping people with heart disease. A new study published in the Annals of Internal Medicine finds that adding ultrasound imaging during the doctor’s assessment of cardiac function could help improve diagnoses and treatments.

These findings come while Purdue University heart imaging researchers are also developing novel strategies to study cardiovascular disease with 4D ultrasound – using 3D space and time. While recent advancements have made 4D ultrasound available to the clinic, the information extracted for patient care remains similar to that provided by its conventional usage as a 2D imaging technique.

Researchers at Purdue are working to extract more comprehensive information from the 4D data that will not only allow better understanding of cardiovascular disease, but also identify improved metrics that can enhance patient care.

4d ultrasound Purdue University heart imaging researchers have developed a new approach to ultrasound – one that uses 4D techniques. (Image provided) Download image

“Our technology helps speed up assessment time and also provide additional information that conventional methods cannot,” said Craig Goergen, the Leslie A. Geddes Associate Professor of Biomedical Engineering in Purdue’s College of Engineering and principal investigator for the Cardiovascular Imaging Research Laboratory. “We think it could eventually help improve our understanding of disease progression and help in developing novel therapeutics.”

Goergen said the Purdue 4D-ultrasound technology automates the acquisition, reconstruction, reorientation and segmentation methods needed to quantify cardiac function and vascular kinematics. A doctor could then examine 4D detailed images of the heart, vessels or other areas of interest. A video showing a 4D image of a heart from Fujifilm VisualSonics Inc. and Goergen is available here.

“The only way to do this previously was to acquire individual images or movies and then reconstruct all the data with computationally intensive techniques,” Goergen said. “Our approach saves many of these steps and helps streamline the process, while also providing useful information that may detect disease initiation at early stages.”

The Purdue team is continuing to test its techniques before moving it into clinics to evaluate patients. Goergen has worked with the Purdue Research Foundation Office of Technology Commercialization for promoting health-related technology.

The technology and research aligns with Purdue's Giant Leaps celebration of the university’s global advancements made in health as part of Purdue’s 150th anniversary. It is one of the four themes of the yearlong celebration’s Ideas Festival, designed to showcase Purdue as an intellectual center solving real-world issues.

About Purdue Research Foundation Office of Technology Commercialization           

The Purdue Research Foundation Office of Technology Commercialization operates one of the most comprehensive technology transfer programs among leading research universities in the U.S. Services provided by this office support the economic development initiatives of Purdue University and benefit the university's academic activities through commercializing, licensing and protecting Purdue intellectual property. The office is managed by the Purdue Research Foundation, which received the 2016 Innovation and Economic Prosperity Universities Award for Innovation from the Association of Public and Land-grant Universities. For more information on licensing a Purdue innovation, contact the Office of Technology Commercialization at otcip@prf.org. For more information about funding and investment opportunities in startups based on a Purdue innovation, contact the Purdue Foundry at foundry@prf.org.The Purdue Research Foundation is a private, nonprofit foundation created to advance the mission of Purdue University.   

Writer: Chris Adam, 765-588-3341, cladam@prf.org 

Source: Craig Goergen, cgoergen@purdue.edu


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