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NIH New R01/U01 Program

Enhancing Purdue’s NIH Research Portfolio

Office of Research
Purdue University
West Lafayette, IN 47907



Standard submission dates are September 17 and February 17 each fall and spring semester.

If due date falls on a weekend, the submission will be accepted through 5:00pm of the following workday. In Spring 2024, the deadline will fall to Monday, February 19th.

Funding Notification

December and May following the fall and spring deadlines

Overview and Purpose

The Office of Research supports an increase in the submission and success rates of new R01/U01 applications from new and established investigators.

The long-term goal is to increase Purdue’s NIH funding portfolio. This program is intended to increase R01/U01 awards by enabling the success of New Projects developed by faculty. An influx of funds in the early stages of a planned R01/U01 project will provide an opportunity to validate specific project aims and acquire strong preliminary data that will increase the probability of success.


Faculty (tenure-track/tenured and research) on the West Lafayette campus are eligible to apply for this program.

Maximum Award

Requests are limited to $50,000 and below.

Application and Submission Process

The program will provide funds within 12-18 months of a planned submission of a R01/U01 application. The faculty should work with their pre-award centers to prepare applications, which must be submitted by the pre-award centers through the InfoReady application portal here:

Faculty are allowed to submit only one application per cycle as a Principal Investigator.

New R01/U01 Applications

Applications must use Arial 11 point font with 0.5 inch margins, single line spacing and must follow the supplied NIH R01/U01 template. Applications should contain the following components:

  1. Abstract (30-line limit)
  2. Introduction and Specific Aims (one-page limit):
    • The goal(s) of the proposed research for which you are requesting these funds
    • Specific aim(s) of the project (not those of the eventual submitted R01)
    • A summary of the expected outcome(s), including the impact you expect these results to have on the competitiveness of the eventual NIH R01 submission
  3. Proposal Narrative (three-page limit):
    • Significance
    • Innovation
    • Approach
    • Anticipated use of funds requested from this program: why these funds are necessary (and sufficient) to write a competitive proposal.
  4. Cited Literature (2-page limit)
  5. Optional Appendix (3-page limit)
    • Can include preliminary data (figures, charts, graphs, tables, etc.)
  6. NIH Biosketch plus current and completed projects for the PI and Co-PI(s)
  7. Any prior summary statements associated with this particular proposal idea that will help to demonstrate why these additional funds/results will address a perceived need
  8. Budget and budget justification: COEUS format for budget page is acceptable.

Incomplete applications and/or applications that do not meet these requirements will be returned without review.

Allowed Costs

  • The intent of this pilot program is to provide funds for student/staff effort, reagents, and services that will enable the needed preliminary data for new R01/U01 applications. The appropriateness of other funding items will be taken on a case-by-case basis and must be well justified.
  • Equipment purchases are not envisioned as part of this pilot program. However, specialized equipment that would bring significant new capabilities to a project may be considered if carefully justified.

Cost Sharing or Matched Funding

Cost-sharing or matched funding is not allowed.


Recipients must submit a new NIH R01/U01 application no later than the submission cycle following the 18-month award. Failure to do so may result in the recipient becoming ineligible to receive future funding from the Office of Research.

Review Criteria

Proposals will be evaluated on the impact they are likely to have on the success of the investigator’s NIH R01/U01 submission. The application should focus on the anticipated aims to be completed in the 18-month period of the New R01/U01 program. Clear and cogent presentation of these aims and how they support the overall R01 application will be weighted heavily. Response to input from the NIH, often in the form of a summary statement, will be viewed very favorably.

Post-Award and Reporting Requirements

The Principal Investigator must submit to the Office of Research (

  1. An email reporting the date the new R01/U01 was submitted
  2. A copy of the review summary of the application when it is received from the NIH.

Additional Information

Questions may be directed to Perry Kirkham ( or Emily Stevenson (

Frequently Asked Questions

  • Why were specific funding mechanisms (e.g., R01/U01) chosen and not others (e.g., R21)?

    The intent is to target only a few, limited, NIH funding mechanisms of high priority for Purdue. The funding mechanisms chosen were based on the results of a review of the distribution of awards within Purdue’s current NIH funding portfolio and considerations of requirements for preliminary data.

  • Are R35 applications eligible as a target funding opportunity for this program?

    No, only R01 or U01 funding mechanisms are eligible target funding opportunities for this program.

  • Will this be a recurring/annual initiative?

    Our goal is to continue offering the program semiannually.

  • What is the goal of this program and whom does it target?

    The goal of the program is to increase the NIH R01/U01 funding portfolio at Purdue. The program targets faculty who are applying for new or additional R01/U01. A goal of the program is to encourage faculty who already have R01 awards or who have a sustained history of federal funding to apply for additional unrelated R01 awards.

  • Who is eligible to apply to the program?

    All faculty (tenure-track/tenured and research) on the West Lafayette campus.

  • Do consulting costs fall under the category of services?


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