In Print: ‘Practical Bioinformatics: A Laboratory Manual’

Michael Gribskov, professor of biological sciences, and his newly published book “Practical Bioinformatics: A Laboratory Manual.”

Publication title

Practical Bioinformatics: A Laboratory Manual

Purdue author

Michael Gribskov

Authors

Michael Gribskov

Sufang Wang

Publisher

Springer Singapore

Publication date

July 30, 2025

About the book (from the publisher)

This book is a lab manual that can be integrated with a bioinformatics course. The field of bioinformatics is advancing at a remarkable rate. With the development of new analytical techniques that make use of the latest advances in machine learning and data science, today’s biologists are gaining fantastic new insights into the natural world’s most complex systems. This book includes a lab-based manual that can assist students handling large biological data. It aims to help students and researchers understand (1) the importance of horizontal transfer in the spread of antibiotic resistance and in biology more broadly; (2) how protein and nucleic acid sequences are used to determine phylogenetic trees and the genetic relationship between organisms; (3) how sequence comparisons can be used to infer protein function; and (4) how to analyze high-throughput sequencing data to do gene expression analysis. This book is valuable for researchers, teachers and students as well as any readers who are interested in bioinformatics.

About the Purdue author

Michael Gribskov is a professor in the Department of Biological Sciences. His research ranges from the evolution, structure and function of macromolecules to the biological networks that control and integrate the development and function of cells. Gribskov’s recent research has centered on gene expression and differential expression of genes and microRNAs in several tumor types, development of new methods for predicting micropeptide coding frames and internal ribosome entry sites, and identifying structural patterns in RNAs and RNA/protein interactions.

About the In Print series To celebrate our faculty’s excellence in scholarship, Purdue Today’s weekly book series highlights faculty expertise across diverse subjects and disciplines. Find out more about the Purdue University Books Initiative and how to suggest a book for the In Print series on the Office of the Provost website

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