In Print: ‘DNA-encoded Library Technology for Drug Discovery’

Publication title

DNA-encoded Library Technology for Drug Discovery

Purdue author

Casey Krusemark

Authors

Guansai Liu

Casey Krusemark

Jin Li

Publisher

Royal Society of Chemistry

Publication date

Feb. 21, 2025

About the book (from the publisher)

DNA-encoded libraries have numerous advantages over traditional screening methods, including easy identification of compounds and the large quantity of compounds that can be screened simultaneously. This book provides a comprehensive guide to the implementation of DNA-encoded library technology (DELT) in drug discovery for screening and hit validation, illustrated with successful case studies. A valuable resource for researchers in drug discovery, this book is complete with successful case studies to illustrate the best practice in implementation and operation of DELT.

About the Purdue author

Casey Krusemark is an associate professor of medicinal chemistry and molecular pharmacology. His research focuses on DNA-encoded chemistry, chemical biology, and proteomics. His work in those areas involves development of novel libraries and selection strategies widely applicable for drug discovery. The lab specifically works on protein-protein interaction inhibitors that are used to help develop therapeutic lead molecules.

About the In Print series

To celebrate our faculty’s excellence in scholarship, Purdue Today’s weekly book series highlights faculty expertise across diverse subjects and disciplines. Find out more about the Purdue University Books Initiative and how to suggest a book for the In Print series on the Office of the Provost website.