Purdue Institute for Drug Discovery

MPTPB Inhibitors

Overview: 

Mycobacterium tyrosine phosphatase B inhibitors for tuberculosis therapy

Status: 

Purdue Faculty: 

Dr. Zhong-Yin Zhang

Research Articles: 

Highly Potent and Selective N-Aryl Oxamic Acid-Based Inhibitors for Mycobacterium Tuberculosis Protein Tyrosine Phosphatase B

Mycobacterial protein tyrosein phosphatases A and B inhibitors augment the bactericidal activity of standard anti-tuberculosis regimen

Discovery and Evaluation of Novel Inhibitors of Mycobacterium Protein Tyrosine Phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic Acid Scaffold

Cefsulodin Inspired Potent and Selective Inhibitors of mPTPB, a Virulent Phosphatase from Mycobacterium tuberculosis

Diversity-Oriented Synthesis for Novel, Selective and Drug-like Inhibitors for a Phosphatase from Mycobacterium Tuberculosis