Purdue Institute for Drug Discovery

LMP744

Overview: 

Small molecule inhibitor of topoisomerase I

Status: 

Purdue Faculty: 

Dr. Mark Cushman

Clinical Trial Information: 

Phase 1 Trial - Indenoisoquinoline LMP744 in Adults With Relapsed Solid Tumors and Lymphomas

Phase 2 Trial - Novel Indenoisoquinolone CMYC/​TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma

Development Partner: 

National Institutes of Health

Gibson Oncology