FM-FolamiR-34a
Overview:
Folate-targeted miRNAs with the ability to escape the endosome to treat cancer. FM-FolamiR-34a is the current lead molecule from the FolamiR platform.
Status:
Purdue Faculty:
Development Partner:
Research Articles:
Enhancing microRNA activity through increased endosomal release mediated by nigericin
New mechanism for release of endosomal contents: osmotic lysis via nigericin-mediated K+/H+ exchange
FolamiRs: Ligand-targeted, vehicle-free microRNA replacement therapy