DUPAmiR
Overview:
Prostate-specific membrane antigen (PSMA)-targeted miRNAs with the ability to escape the endosome to treat prostate cancer
Status:
Purdue Faculty:
Development Partner:
LigamiR Therapeutics
Research Articles:
Enhancing microRNA activity through increased endosomal release mediated by nigericin
New mechanism for release of endosomal contents: osmotic lysis via nigericin-mediated K+/H+ exchange