Purdue Institute for Drug Discovery

DESI diagnostic

Overview: 

DESI diagnostic is a desorption electrospray ionization mass spectrometer and methodology that can detect oncometabolites from small tissue biopsies in the operating room and improve diagnostic accuracy.

Status: 

Purdue Faculty: 

Dr. Graham Cooks

Research Articles: 

Intraoperative assessment of isocitrate dehydrogenase mutation status in human gliomas using desorption electrospray ionization–mass spectrometry

Intraoperative Detection of Isocitrate Dehydrogenase Mutations in Human Gliomas using a Miniature Mass Spectrometer

Lipid and metabolite profiles of human brain tumors by desorption electrospray ionization-MS.

Intraoperative assessment of tumor margins during glioma resection by desorption electrospray ionization-mass spectrometry.