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Purdue Institute of Inflammation, Immunology and Infectious Disease
February 28, 2024
1:30 PM - 2:30 PM
MJIS 1001


Multiple proteinaceous alphavirus receptors have been discovered in recent years, including mammalian Mxra8, used by chikungunya and other members of the Semliki Forest virus family; avian Mxra8, used by the Western equine encephalitis virus family; LDLRAD3, used specifically by Venezuelan equine encephalitis virus; and VLDLR, used by Eastern equine encephalitis and select Semliki Forest family viruses. In this presentation we will explore the structural basis of these alphavirus/receptor interactions as well discuss the development of decoy receptors capable of neutralizing infections.

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Purdue University, West Lafayette, IN 47907 (765) 494-4600

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