Winning Proposals

Solving problems previously reserved to quantum computing with Purdue's p-bits

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PI: Joerg Appenzeller, Barry M. and Patricia L. Epstein Professor of Electrical and Computer Engineering; Scientific Director of Nanoelectronics in the Birck Nanotechnology Center

Overview: We are all familiar with the amazing performance of the modern smartphone, bowered by millions of digital circuits that implement "hard logic."  However, recently, the discussion about problems that cannot be solved with conventional hardware and computing approaches has led to a vast research initiative worldwide on quantum computing.  

 

 

 

 

Revolutionizing the Development and Manufacturing of Next-Generation Biologics

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PI: Rainer Fischer, President's Fellow in Life Sciences

Overview: The aim of this project is to revolutionize the discovery and development of new antibodies as proof-of-concept for the broader field of biologics.  Antibodies protect us against diseases, but current antibody discovery methods are time-consuming and expensive, and the antibodies are not always effective because they are selected artificially.  Fischer and his team will work to integrate breakthrough science, data analytics, large-scale computing and engineering with clinical needs in infectious disease by completely disrupting and revolutionizing today's laborious and inefficient antibody discovery and development pipeline.

 

 

 

From Cell Cultures to Community Cultures:  Brining Precision Health to Autism

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PI: Bridgette Kelleher, Assistant Professor of Physchological Sciences, Clinical Psychology and Neuroscience

Overview: Imagine a world in which a child's risk for autism could be quantified in the first days of life, permitting protection during critical periods when the brain is most malleable though symptoms are not yet apparent. Imagine a world in which methods for promoting healthy neurodevelopment are personalized to an individuals genetic, environmental and cultural profile, optimizing outcomes for children with autism and their communities.  Tonnsen and her team are working to develop a novel patient-centered omnityping assay, The Purdue Omnityping Kit for Individualized Treatment (POcKIT), that integrates genetic, biological, nutritional, and environment information to quantify an individuals risk for autism symptoms prior to the onset of clinical signs, and determine and optimized treatment approach tailored to the individuals genetic, environmental, and cultural background.