Faculty Associates

Connie M. Weaver

Contact Information
Email: weavercm@purdue.edu
Distinguished Professor Emerita, Department of Nutrition Science

PubMed Listing
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PhD Florida State University Nutrition 1978

Research Interests

Nutrition; calcium metabolism/bone health

Teaching Interests

Minerals, Executive in the Classroom


Alliance for Potato Research and Education
Tate & Lyle
National Institutes of Health

Selected Publications

Whisner CM, Martin BR, Nakatsu, CH, Story JA, MacDonald-Clarke CJ, McCabe LD, McCabe GP, Weaver CM. Soluble corn fiber increases calcium absorption associated with shifts in the gut microbiome. A randomized dose-response trial in free-living pubertal girls. J Nutr, In press, 2016.

Bailey RL, Parker EA, Rhodes DG, Goldman JD, Clemens JC, Moshfegh AJ, Thuppal SV, Weaver CM. Estimating sodium and potassium intakes and their ratio in the American diet: Data from the 2011-2012 NHANES. J Nutr 2016 doi: 10.3945/jn.115.221184

Ferira AJ, Laing EM, Hausman DB, Hall DB, McCabe GP, Martin BR, Hill KM, Warden SJ, Weaver CM, Peacock M, Lewis RD. Vitamin D supplementation effects on insulin sensitivity and resistance in early pubertal white and black children. J Clin Endocrinol Metab, In Press, 2016.

Bailey RL, Parker EA, Rhodes DG, Goldman JD, Clemens JC, Moshfegh AJ, Thuppal SV, Weaver CM. Estimating sodium and potassium intakes and their ratio in the American Diet: Data from the 2011-2012 NHANES. J Nutr, 2016 doi:10.3945/jn.115.221184.

Bailey RL, Looker AC, Lu Z, Fan R, Eicher-Miller HA*, Fakhouri TH, Gahche JJ, Weaver CM, Mills JM. B-vitamins and bone mineral density and risk of lumbar osteoporosis in older females in the U.S. Am J Clin Nutr 102:687-954, 2015.

Jackson GS, Einstein JA, Kubley T, Martin BR, Weaver CM, Caffee MW. Biomedical graphite and CaF2 preparation and measurement at PRIME Lab. Nucl Instr and Meth in Phys Res B. 361:358-362, 2015.

Phillips-Eakley AK, McKenney-Drake ML, Bahls M, Newcomer SC, Radcliffe JS, Wastney ME, Van Alstine WG, Jackson G, Alloosh M, Martin B, Sturek M, Weaver CM. Effect of high-calcium diet on coronary artery disease in Ossabaw miniature swine with metabolic syndrome. J Am Heart Assoc e001620, 2015.

Schafer AL, Weaver CM, Black DM Wheeler AL, Chang H, Szefc GV, Steward L, Rogers SJ, Carter JT, Posselt AM, Shoback DM, Sellmeyer DE. Intestinal calcium absorption decreases dramatically after gastric bypass surgery despite optimization of vitamin D status. J Bone Miner Res 30:1377-1385, 2015.

Pawlowski J, Martin B, McCabe G, McCabe L, Jackson G, Peacock M, Barnes S, Weaver CM. Impact of equol producing capacity and soy isoflavone profiles of supplements on bone calcium retention in postmenopausal women: a partially randomized crossover trial. Am J Clin Nutr 102:695-703, 2015

Whisner CM, Martin BR, Nakatsu CH, McCabe GP, McCabe LD, Peacock M, Weaver CM. (2014). Soluble corn fiber affects short-term calcium absorption in adolescent boys and girls: A randomized controlled trial using dual stable isotopic tracers, Br J Nutr, 12(3):446-456.

Park CY, Lee WH, Fleet JC, Allen MR, McCabe GP, Walsh DM, Weaver CM. (2014). Calcium and vitamin D intake maintained from pre-ovariectomy independently affect calcium metabolism and bone properties in Sprague Dawley rats.Osteoporos Int, 25(7):1905-15.

Pawlowski J, Martin B, McCabe G, Ferruzzi M, Weaver, C. (2014). Polyphenolic-rich extracts of plum, blueberry, grape seed, soy, and grape improve bone calcium retention in ovariectomized Sprague Dawley rats.J Ag Food Chem, 62(26):6108-17.

Palacios C, Martin BR, McCabe GP, McCabe L, Peacock M, Weaver CM. (2014 ). Dietary calcium requirements do not differ between Mexican American boys and girls.J Nutr, 144(8):1167-73.

Weaver CM. (2014). Calcium Supplementation: Is protecting against osteoporosis counter to protecting against cardiovascular disease.Current Osteoporosis Reports, 12(2):211-21.

Weaver CM. (2014). Bioactive foods and ingredients for health.Adv Nutr, 5:3065-3115.

Moseley, K., Weaver, C., Appel, L., Sebastian, A., & Sellmeyer, D. E. (2013). Potassium citrate supplementation results in sustained improvement in calcium balance in older men and women. Journal of Bone and Mineral Research, 28, 497-504.

Simon, R. R., Borzellaeca, J. F., DeLuca, H. F., & Weaver, C. M. (2013). Safety assessment of the post-harvest treatment of button mushrooms (Agaricus bisporus) using ultraviolet light. Food and Chemical Toxicology, 56, 278-289.

Warden, S. J., Hill, K. M., Ferira, A. J., Laing, E. M., Martin, B. R., Hausman, D. B., Weaver, C. M., Peacock, M., & Lewis. R. D. (2013). Racial differences in cortical bone and biochemical variables in black and white children in the early stages of puberty. Osteoporosis International, 24, 1869-79.

Whisner CM, Martin BR, Schoterman MHC, Nakatsu CH, McCabe LD, McCabe GP, Wastney ME, van den Heuvel EGHM, Weaver CM. (2013). Galacto-oligosaccharides increase calcium absorption and gut bifidobacteria in young girls: A double blind crossover trial. Br J Nutr 14:1-12. PMID:23507173

Hill KM, Martin BR, Wastney ME, McCabe GP, Moe SM, Weaver CM, Peacock M. (2013). Oral calcium carbonate affects calcium but not phosphorus balance in stage 3-4 chronic kidney disease. Kidney Intl 83:959-66. PMID: 23254903

Osborne, D. L., Weaver, C. M., McCabe, L. D., McCabe, G. P., Novotny, R., Van Loan, M. D., Going, S., Matkovic, V., Boushey, C. J., & Savaiano, D. A. (2012). Body size and pubertal development explain ethnic differences in structural geometry at the femur in Asian, Hispanic, and white early adolescent girls living in the U.S. Bone, 51:888-95.

Wastney, M., Lee, W., Jackson, G. S., Alloosh, M., Sturek, M., Lachcik, P., Peacock, M., Martin, B., & Weaver, C. M. (2012). Soft tissue calcification in the Ossabaw miniature pig: Experimental and kinetic modeling studies. Osteoporosis International, 24(7), 2123-6.

Hill, K. M., Jonnalagadda, S. S., Albertson, A. M., Josh, N. A., & Weaver, C. M. (2012). Top food sources contributing to vitamin D intake and the association of ready-to-eat cereal and breakfast consumption habits to vitamin D intake in Canadians and United States Americans. Journal of Food Science, 77, H170-5.

Hill, K. M., Laing, E. M., Hausman, D. B., Acton, A., Martin, B. R., McCabe, G. P., Weaver, C. M., Lewis, R. D., & Peacock, M. (2012). Bone turnover is not influenced by serum 25-hydroxyvitamin D in pubertal healthy black and white children. Bone, 51, 795-799.

Legette, L. L., Lee, W. H., Martin, B. R., Story, J. A., Campbell, J. K., & Weaver, C. M. (2012). Enhanced magnesium absorption and inulin-based fibers exert chronic effects on calcium utilization in a postmenopausal rodent model. Journal of Food Science, 77:89-94.

Legette LL, Lee WH, Martin BR, Story JA, Arabshahi A, Barnes S, Weaver CM. (2011). Genistein, a phytoestrogen, improves total cholesterol, and Synergy, a prebiotic, improves calcium utilization, but there were no synergistic effects. Menopause 18(8):923-31.

Lee W-H, Wastney M E, Jackson GS, Martin BR, Weaver CM.(2011). Interpretation of 41Ca data using compartmental modeling in post-menopausal women. Anal Bioanal Chem 399:1613-1622 PMID: 21152905S

Lee WH, McCabe G, Martin B, Weaver CM. (2011). Simple isotopic method using oral stable or radioactive tracers for estimating fractional calcium absorption in adult women. Osteoporos Int 22:1829-1834. PMID: 20936404

Cheong J, Gunaratna N, McCabe G, Jackson G, Kempa-Steczko A, Weaver C. (2011). Bone seeking labels as markers for bone turnover: Validation of urinary excretion in rats. Osteoporosis Intl. 22:153-157.

O'Connell DN, Weinheimer EM, Martin BR, Weaver CM, Campbell WW. (2011). Water turnover assessment in overweight adolescents. Obesity 19:292-297.

Lee W, McCabe GP, Martin BR, Weaver. (2010). Validation of a simple isotope method for estimating true calcium fraction absorption in adolescents. Osteoporos Int 22:159-166.

Klein MA, Nahin RL, Messina MJ, Rader JI, Thompson LU, Badger TM, Dwyer JT, Kim YS, Pontzer CH, Starke-Reed PE, and Weaver C. (2010). Guidance from an NIH Workshop on Designing, Implementing, and Reporting Clinical Studies of Soy Interventions. J Nutr 140:1192S-1204S. PMID: 20392880

Reinwald S, Mayer LP, Hoyer PB, Turner CH, Barnes S, Weaver CM. (2010). A longitudinal study of the effect of genistein on bone in two different murine models of diminished estrogen-producing capacity. J Osteoporosis. PMID:20948578 doi:10.4061/2010/145170.

Shahnazari M, Burr DB, Lee W-H, Martin BR, Weaver CM. (2010). Cross-calibration of 45calcium kinetics against dynamic histomorphometry in a rat model to determine bone turnover. Bone 46:1238-43. PMID: 20149909

Wu L, Martin BR, Braun MM, Wastney ME, McCabe GP, McCabe LD, DiMeglio LA, Peacock M, Weaver CM. (2010). Calcium requirements and metabolism in Chinese American boys and girls. J Bone Miner Res. 25:1842-1849. PMID: 20205166

Hill KM, McCabe GP, McCabe LD, Gordon CM, Abrams SA, Weaver CM. (2010). An inflection point of serum 25-hydroxyvitamin D for maximal suppression of parathyroid hormone is not evident from multi-site pooled data in children and adolescents. J Nutr 140:1938-1988.

Weaver CM, Martin BR, Story JA, Hutchinson I, Sanders L. (2010). Novel fibers increase bone calcium content and strength beyond efficiency of large intestine fermentation. J Ag Food Chem. 58:8952-8957.

Palacios C, Wigertz K, Martin BR, Braun M, Pratt JH, Peacock M, Weaver CM. (2010). Racial differences in potassium homeostasis in response to differences in dietary sodium in girls. Am J Clin Nutr 91(4):597-603.

Weaver CM, Martin BR, Jackson GS, McCabe GP, Nolan JR, McCabe LD, Barnes S, Reinwald S, Boris ME, Peacock M. (2009). Antiresorptive effects of phytoestrogen supplements compared to estradiol or Risedronate in postmenopausal women using 41Ca methodology. J Clin Endocrinol Metab. 94(10): 3798-3805. PMID: 19584189

Weaver CM, Janle E, Martin B, Browne S, Guiden H, Lachcik P, Lee W-H. (2009). Dairy versus calcium carbonate in promoting peak bone mass and bone maintenance during subsequent calcium deficiency. J Bone Miner Res. 24:1411-1419. PMID: 19309298

Weaver CM, Barnes S, Wyss JM, Kim H, Morre DM, Morre DJ, Simon JE, Lila MA, Janle EM, Ferruzzi MG. (2007). Botanicals for age-related diseases: from field to practice. Am J Clin Nutr 87:493S-497S

Cheong, J.M.K., Martin, B.R., Jackson, G.S., Elmore, D., McCabe, G.P., Nolan, J.R., Barnes, S., Peacock, M., Weaver, C.M. (2007). Soy isoflavones do not affect bone resorption in postmenopausal women: A dose response study using a novel approach with 41Ca. J. Clin. Endocrin. Metab. 92:577-585. PMID: 17148567

Cai DJ, Zhao Y, Glasier J, Cullen D, Barnes S, Turner CH, Wastney M, Weaver C. (2005). Comparative effect of soy protein, soy isoflavones and 17b-estradiol on bone metabolism in adult ovariectomized rats. J Bone Miner Res. 20:828-39. PMID: 15824856.

Spence LA, Lipscomb ER, Cadogan J, Martin B, Wastney ME, Peacock M, Weaver CM. (2005). The effect of soy protein and soy isoflavones on calcium metabolism and renal handling in postmenopausal women: A randomized cross over study. Am J Clin Nutr. 81:916-922. PMID: 15817872.

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