Faculty Associates

Jennifer L. Freeman

Contact Information
Email: jfreema@purdue.edu
Office: HAMP-1163D Map
Phone: 765-494-1408
Fax: 765-496-1377
Homepage: Homepage
Associate Professor of Toxicology

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Education


PhD University of Illinois at Urbana-Champaign Enviromental Toxicology and Molecular Cytogenetics 2005

Research Interests


Genetic and epigenetic mechanisms of toxicity of the developmental origin of adult disease from low dose exposure to environmental chemicals

Teaching Interests


Toxicology and Environmental Health

Grants


2019 - National Institute for Occupational Safety and Health, Occupational and Environmental Health and Safety Education and Research Center, University of Illinois at Chicago
2018 - UNSA NEXUS / Arequipa Nexus Institute for Food, Energy, Water, and the Environment
2018 - Purdue Executive Vice President for Research and Partnerships
2016 - National Institute for Occupational Safety and Health, Occupational and Environmental Health and Safety Education and Research Center, University of Illinois at Chicago

Selected Publications


Horzmann, K.A., A.M. Portales, K.G. Batcho, and J.L. Freeman. 2020. Developmental toxicity of trichloroethylene in zebrafish (Danio rerio). Environmental Science: Processes & Impacts. doi: 10.1039/c9em00565j.

Sanchez, O., L. Lin, C. Bryan, J. Xie, J.L. Freeman, and C. Yuan. 2020. Profiling epigenetic changes in human cell lines induced by atrazine exposure. Environmental Pollution. 258:113712. DOI: 10.1016/j.envpol.2019.113712

Cassar, S., I. Adatto, J.L. Freeman, J.T. Gamse, I. Iturria, C. Lawrence, A. Muriana, R.T. Peterson, S. Van Cruchten, and L.I. Zon. 2020. Use of zebrafish in drug discovery toxicology. Chemical Research in Toxigology. doi: 10.1021/acs.chemrestox.9b00335.

Pitchai, A., R.K. Rajaretinam, and J.L. Freeman. 2019. Zebrafish as an emerging model for bioassay-guided natural product drug discovery in neurological disorders. Medicines. 6(2):61.

Dorman, D.C., H.A. Barton, K. Blackburn, J. Bucher, J.L. Daniels, J.L. Freeman, K. Mansouri, C. Messerlian, D.M. Reif, G.M. Solomon, and C. Yang. Committee to Develop a Scoping Plan to Assess the Hazards of Organohalogen Flame Retardants. National Academies of Sciences, Engineering, and Medicine. 2019. A Class Approach to Hazard Assessment of Organohalogen Flame Retardants. Washington, DC: The National Academies Press. https://doi.org/10.17226/25412.

Horzmann, K.A. and J.L. Freeman*. 2018. Making waves: New developments in toxicology with the zebrafish. Toxicol. Sci. 163:5-12.

Caballero-Gallardo, K., S.E. Wirbisky-Hershberger, J. Olivero-Verbel, J. de la Rosa, and J.L. Freeman. 2018. Embryonic exposure to an aqueous coal dust extract results in gene expression alterations associated with development and function of connective tissue and the hematological system, immunological and inflammatory disease, and cancer in zebrafish. Metallomics. 10:463-473

Horzmann, K.A., L.S. Reidenbach, D.H. Thanki, A.E. Winchester, B.A. Qualizza, G.A. Ryan, K.E. Egan, V.E. Hedrick, T.J.P. Sobreira, S.M. Peterson, G.J. Weber, S.E. Wirbisky-Hershberger, M.S. Sepulveda, and J.L. Freeman. 2018. Embryonic atrazine exposure elicits proteomic, behavioral, and brain abnormalities with development time specific gene expression signatures. Journal of Proteomics. 186:71-82.

Lee, J., K.A. Horzmann, and J.L. Freeman. 2018. An embryonic 100 ug/L lead exposure results in sex-specific expression changes in genes associated with the neurological system in female or cancer in male zebrafish brains. Neurotox. Teratol. 65:60-69.

Wasel, O. and J.L. Freeman. 2018. Comparative assessment of tungsten toxicity in the absence or presence of other metals. Toxics. 6:66

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