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Purdue Institute for Drug Discovery Retreat

Purdue Institute for Drug Discovery
May 10, 2019
8:30 AM - 2:00 PM
Beck Agricultural Center


The Purdue University Institute for Drug Discovery invites you to attend a retreat to foster collaborations and discuss how best PIDD can serve affiliated faculty and drug discovery/development research. 

Purdue Institute for Drug Discovery – Retreat Agenda

Friday, May 10th, 2019

Beck Ag Center

8:00 – 8:30          Breakfast

8:30 – 8:45          Welcome and Institute Update Dr. Zhong-Yin Zhang

8:45 – 9:00          "Basics of intellectual property and IP licensing in the life sciences" Joe Kasper 

9:00 – 10:00        Speaking Session 1 – Medicinal Chemistry & Formulations

                                Moderated by:  Herman Sintim and Yoon Yeo

                                1)  Lynne Taylor - "TBA"

                                2) Rodolfo Pinal - "Drug solubility and related properties as information tools during early drug


                                3) Herman Sintim - “One-flask syntheses and biological evaluations of non-covalent and

                                                               selective kinase inhibitors with picomolar affinities”

                               4) Rong Huang - “Development of potent and specific inhibitors for methyltransferases towards

                                                           new drug discovery”

10:00 – 10:15     Break

10:15 – 11:15     Speaking Session 2 – Structural Biology and Biophysics

                                Moderated by:  Robert Stahelin and John Tesmer

                                1) Danzhou Yang - "Targeting DNA G-quadruplexes for anticancer drug design”

                                2) Yu-Chen Yen - "Structure-based drug design of selective BACE2 inhibitors for the

                                                              treatment of type II diabetes”

                                3) Leifu Chang - "Unraveling the molecular mechanisms of anti-CRISPR proteins by cryo-EM"

11:15 – 12:15     Speaking Session 3 – Preclinical Models for Drug Discovery

                                Moderated by:  Bumsoo Han and Riyi Shi

                                1) Robert Stahelin - “Assembly and Budding of Filoviruses as a Site of Drug Development for

                                                                 infectious diseases”  

                                2) Yang Yang/Riyi Shi - “A combined In vitro and In vivo model of pain assessment for drug


                                3) Michael Childress - “Large animal cancer as a clinical relevant model for drug discovery”

12:15-12:30         MI-BIO initiative - Bryan Boudouris

12:30 – 12:45     Pickup Lunch for Working Lunch Discussion Sessions

12:45 – 1:45        Concurrent Discussion Sessions

  1. How to better promote collaboration among faculty and raise the prominence of Drug Discovery at Purdue

               Moderated by Carol Post and Elsje Pienaar

       2. Infrastructure needs and how best to assist PIDD members to translate lab discoveries to the clinic

               Moderated by Daniel Flaherty and Wen Jiang

       3. How to better work with other institutes and centers on campus

               Moderated by Emily Dykhuizen and Marxa Figueiredo

1:45 – 2:00          Report from Session Moderators


Register HERE



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