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PI4D Distinguished Lecture - Dr. Eckard Wimmer

Purdue Institute of Inflammation, Immunology and Infectious Disease
April 4, 2018
2:30 PM - 3:30 PM
MRGN 121

Description

Dr. Eckard Wimmer

Distinguished Professor

Department of Molecular Genetics and Microbiology

Stony Brook University School of Medicine

 

"An Impact of de novo Synthesizing Poliovirus: Recoding Arboviruses for Vaccine Development"

 

The chemical test-tube synthesis of poliovirus, published 2002, caused an uproar world-wide. It showed that viruses not only exist as infectious particles in nature but viruses can be recreated in laboratories with the computer as parent. However, the cell-free synthesis also allows to alter the viral genome to an extent that has never been possible before.

I will present examples of novel genetic studies of RNA viruses. Selecting codon pair deoptimization, a little known genetic phenomenon functioning in multiple (all?) taxa, the possible in silico generation of dengue viruses as new vaccine candidates will be discussed.

Dr. Wimmer has been awarded various honors and awards throughout his career.  Just a few are: 2014 Loeffler-Frosch Medal by the Society of Virology of Germany, Austria and Switzerland; 2012 Member, National Academy of Sciences; 2012 Robert-Koch Medal in Gold by the Robert-Koch Stiftung, Berlin, Germany; The 2010 Beijerinck Price in Virology, by The Royal Netherlands Academy of Arts and Sciences; Fellow of the American Association for the Advancement of Science (2008); Lifetime Achievement Award, The Research Foundation of the State University of New York, April 2008; Distinguished Professor of the State University of New York at Stony Brook (2002); Highly Cited Researcher 1980 –present (ISIHighlyCited.com); Fellow, Deutsche Akademie der Naturforscher Leopoldina von 1652 (1998); Fellow, American Academy for Microbiology (1994); Alexander von Humboldt-Forschungspreis (1996)

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