When polycystic ovary syndrome (PCOS) was renamed to polyendocrine metabolic ovarian syndrome (PMOS) in May 2026, understanding of the syndrome seemingly took a step forward overnight. However, the condition, which is a hormonal disorder affecting women and is the leading cause of infertility worldwide, according to the World Health Organization, has often gone understudied. Direct causes of the condition remain unknown.
Claire Miller, a graduate student in the Purdue University Department of Psychological Sciences (PSY), recently published her master’s thesis centered around PMOS with findings that support its renaming through modeling dehydroepiandrosterone (DHEA) as a precursor for the syndrome. In this study, which was published in Physiology & Behavior, Miller’s model produced excess testosterone and irregular menstrual cycles but not the polycystic ovaries that are the original namesake of the disorder.
Written By: Rebecca Hoffa, rhoffa@purdue.edu When polycystic ovary syndrome (PCOS) was renamed to polyendocrine metabolic ovarian syndrome (PMOS) in May 2026, understanding of the syndrome seemingly took a step forward overnight. However, the condition, which is a hormonal disorder affecting...