James C. Fleet
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Contact Information Email: fleet |at| purdue.edu Office: STON G-1D Map Phone: (765) 494-0302 Fax: (765) 494-0906 Homepage: Homepage |
Distinguished Professor of Nutrition Science PubMed Listing Google Scholar Listing View Vita
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Education
B.S. Cornell University Animal Science 1981
M.S. University of Delaware Animal Nutrition 1984
Ph.D. Cornell University Nutritional Biochemistry 1988
Research Interests
Vitamin D, impact on calcium metabolism, prostate cancer, Regulation of mineral metabolism, Intestinal biology, Impact of aging on biological function
Teaching Interests
Presentation skills for Graduate students (FN695) Nutritional Biochemistry and Physiology I (FN590B) Nutrition and Genetics (FN special topics course)
Grants
National Institutes of Health
US Veterans Administration
US Department of Agriculture
Private industry and foundations
Publications
Xu, Y. and Fleet, J.C. (2009) Complete recovery of the VDR knockout phenotype by villin-directed expression of VDR in the intestine. Gastroenterology Accepted.
Cui, M., Klopot, A., and Fleet, J.C., (2009) The impact of differentiation on 1,25 dihydroxyvitamin D-mediated gene expression in the enterocyte-like cell line, Caco-2. J. Cell Physiol. 218:113-21.
Cui, M., Zhao, Y., Hance, K.W., and Fleet, J.C. (2009) MAPK signaling enhances 1,25 dihydroxyvitamin D-mediated CYP24 gene expression in the enterocyte-like cell line, Caco-2. A differential role for Ets1 phosphorylation depending upon the state of differentiation. J. Cell Physiol. 219:132-142.
Fleet, J.C., Gliniak, C., Zhang, Z., Xue, Y., Barzan, K., McCreedy, R., and Adedokun S.A. (2008) Serum metabolite profiles and target tissue gene expression define the impact of cholecalciferol intake on calcium metabolism in rats and mice. J. Nutr. 138:1114-1120.