Faculty Associates

James C. Fleet

Contact Information
Email: fleet |at| purdue.edu
Office: STON G-1D Map
Phone: (765) 494-0302
Fax: (765) 494-0906
Homepage: Homepage
Distinguished Professor of Nutrition Science

PubMed Listing
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B.S. Cornell University Animal Science 1981
M.S. University of Delaware Animal Nutrition 1984
Ph.D. Cornell University Nutritional Biochemistry 1988

Research Interests

Vitamin D, impact on calcium metabolism, prostate cancer, Regulation of mineral metabolism, Intestinal biology, Impact of aging on biological function

Teaching Interests

Presentation skills for Graduate students (FN695) Nutritional Biochemistry and Physiology I (FN590B) Nutrition and Genetics (FN special topics course)


National Institutes of Health
US Veterans Administration
US Department of Agriculture
Private industry and foundations


Xu, Y. and Fleet, J.C. (2009) Complete recovery of the VDR knockout phenotype by villin-directed expression of VDR in the intestine. Gastroenterology Accepted.

Cui, M., Klopot, A., and Fleet, J.C., (2009) The impact of differentiation on 1,25 dihydroxyvitamin D-mediated gene expression in the enterocyte-like cell line, Caco-2. J. Cell Physiol. 218:113-21.

Cui, M., Zhao, Y., Hance, K.W., and Fleet, J.C. (2009) MAPK signaling enhances 1,25 dihydroxyvitamin D-mediated CYP24 gene expression in the enterocyte-like cell line, Caco-2. A differential role for Ets1 phosphorylation depending upon the state of differentiation. J. Cell Physiol. 219:132-142.

Fleet, J.C., Gliniak, C., Zhang, Z., Xue, Y., Barzan, K., McCreedy, R., and Adedokun S.A. (2008) Serum metabolite profiles and target tissue gene expression define the impact of cholecalciferol intake on calcium metabolism in rats and mice. J. Nutr. 138:1114-1120.

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