Project ROS signaling in growth cone motility Program First Year Investigators Undergraduate Research Program Term 12-Month 2023 Status Closed Research Area Cellular Neurobiology Description This research project aims at gaining a better understanding of the role of reactive oxygen species (ROS) in regulating neuronal growth cone motility. ROS have been shown to control cell motility; however, the spatiotemporal changes of ROS in the cell are not well characterized. Furthermore, the target molecules controlled by ROS that regulate growth cone movement need further investigation. We expect that the findings from this study will not provide new insights into normal neuronal development but also guide the design of new therapeutics for neuronal regeneration. Supervisor Daniel M Suter Mentor Type of work required Primary neuronal cell culture, live fluorescence imaging, quantitative image analysis, writing progress reports, presenting data Websites https://suterlab.bio.purdue.edu/ Qualifications GPA 3.5 or higher, major in Biology, Biochemistry, Neurobiology or related fields, interests in microscopy, attention to details Credit Hours 2 Weekly Hours 9 (estimated)