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Michael R. Ladisch, PhD

Distinguished Professor and Director
Laboratory of Renewable Resources Engineering
Purdue University
Potter Engineering Center, Room 216
500 Central Drive
West Lafayette, Indiana 47907-2022

Phone: 765-494-7022

Fax: 765-494-7023


Michael R. Ladisch is Director of the Laboratory of Renewable Resources Engineering (LORRE), and Distinguished Professor of Agricultural and Biological Engineering, with a joint appointment in the Weldon School of Biomedical Engineering.  His BS (1973) is from Drexel University, with MS (1974) and PhD (1977) from Purdue University, all in Chemical Engineering.  He was Chief Technology of Mascoma Corporation from 2007 to 2013, and is currently a member of the Scientific Advisory Board of Agrivida, and the Board of Directors for the Foundation of Food and Agricultural Research.

Dr. Ladisch has 40 years’ experience in research in biofuels, renewable resources, bioseparations, and biotechnology.  He has authored a graduate textbook (Bioseparations Engineering, Wiley, 2001), and co-authored an undergraduate textbook (Modern Biotechnology, Wiley, July, 2009), as well as numerous publications and patents.  He serves on the editorial boards of journals including Biotechnology and Bioengineering, Bioresource Technology, AIChE J., Enzyme and Microbial Technology, Industrial Biotechnology, Biotechnology Progress, Biotechnology for Biofuels, and J. Biological Engineering.

The American Institute of Chemical Engineers awarded him The Food, Pharmaceutical and Bioengineering Division Award, in 2001, and named him as one of The 100 Engineers of the Modern Era, in 2008.  He received The Marvin J. Johnson Award in Biochemical Technology, from The American Chemical Society, in 2002; the Paul Dana Biofuels Award in 2006, and The Agricultural Team (Biosensor Detection Team) and Outstanding Chemical Engineer Awards, at Purdue University, in 2006.  He received The Charles Scott Award of the Society of Industrial Microbiology, in 2009.  He was named  Fellow of the American Institute of Medical and Biological Engineering (AIMBE) in 1994, the ACS and AAAS in 2011, and the National Academy of Inventors, in 2013.   Dr. Ladisch was elected to the National Academy of Engineering in 1999.


Modern Biotechnology Textbook

Modern Biotechnology: Connecting Innovations in
Microbiology and Biochemistry to Engineering Fundamentals

Solutions Manual Available Upon Request

Hardback (ISBN 978-0-470-11485-8)

Available at: Amazon.com, Barnes & Noble

John Wiley & Sons, Inc.
Hoboken, New Jersey


Bioseparations Engineering Textbook

Bioseparations Engineering: Principles, Practice, and Economics

Solutions Manual Available Upon Request

Hardback (ISBN 0-471-24476-7)

Available at: Amazon.com, Barnes & Noble

John Wiley & Sons, Inc.
New York, NY

Relevant Publications:

Bonawitz, N. D., J. I. Kim, Y. Tobimatsu, P. N. Ciesielski, N. A. Anderson, E. Ximenes, J. Maeda, J. Ralph, B. S. Donohoe, M. R. Ladisch, C. Chapple, "Disruption of Mediator Rescues the Stunted Growth of a Lignin-Deficient Arabidopsis Mutant," Nature, 509, 376-380 (2014).

Kim, Y., T. Kreke, and M. R. Ladisch, "Reaction Mechanisms and Kinetics of Xylo-oligosaccharide Hydrolysis by Dicarboxylic Acids," AIChE Journal, 59(1), 188-199 (2013).

Kim, Y., T. Kreke, R. Hendrickson, J. Parenti, M. R. Ladisch, "Fractionation of Cellulase and Fermentation Inhibitors from Steam Pretreated Mixed Hardwood," Bioresource Technology, 135, 30-38 http://dx.doi.org/10.1016/j.biortech.2012.10.130 (2013).

Li, X., E. Ximenes, M. Amalaradjou, H. Vibbert, K. Foster, J. Jones, X. Liu, A. Bhunia, and M. Ladisch, "Rapid Sample Processing for Foodborne Pathogen Detection via Cross-Flow Microfiltration," Applied and Environmental Microbiology, 79(22), 7048-7054 (2013).

Kim, Y., T. Kreke, N. Mosier, and M. Ladisch, "Severity Coefficients for Subcritical Hot Water Pretreatment of Hardwood Chips," Biotechnology & Bioengineering, 111(2), 254-263 (2013).

Li, Xu, E. Ximenes, Y. Kim, M. Slininger, R. Meilan, M. Ladisch, and C. Chapple, "Lignin Monomer Composition Affects Arabidopsis Cell-wall Degradability After Liquid Hot Water Pretreatment," Biotechnology for Biofuels, 3, 27 (2010).

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