Publications from the Zhang Research Group

  1. Silic M.R., Zhang G#. (2018). Visualization of Cellular Electrical Activity in Zebrafish Early Embryos and Tumors. JOVE, 134: e57330, doi:10.3791/57330

  2. Kumari K., Silic M.R., Jones-Hall Y.L., Nin-Velez A., Yang J.Y., Mittal S.K., Zhang G#. (2018). Identification of RECK as an evolutionarily conserved tumor suppressor gene for zebrafish malignant peripheral nerve sheath tumors. Oncotarget, 9:23494-23504.

  3. Huang S., Shen, Y.J. Pham D., Jiang L., Kaplan, M.H., Zhang, G., Sun J. (2017). IRF4 modulates CD8 T cell sensitivity to IL-2 family cytokines. ImmunoHorizons, 1: 92-100. DOI:

  4. Ahi,Y.S., Hassan, A.O., Vemula, S.V., Li, K., Wen Jiang, W., Zhang, G. and Mittal, S.K. (2017). Adenoviral E4 33K protein interacts with virus packaging components and may serve as the putative portal. Scientific Reports, 7: 7582. DOI:10.1038/s41598-017-07997-w

  5. Zhang, R., Huang, S.Y., Li, K., Li, Y.H., Hsu, W.H., Zhang, G., Chang, C.J., Yang, J.Y. (2017). Dual degradation signals destruct GLI1: AMPK inhibits GLI1 through β-TrCP-mediated proteasome degradation. Oncotarget. doi: 10.18632/oncotarget.17769.

  6. Cui Z, Shen, Y.J., Chen K.H., Mittal, S.K., Yang, J.Y., and Zhang, G. (2017). KANK1 inhibits cell growth by inducing apoptosis through regulating CXXC5 in human malignant peripheral nerve sheath tumors. Scientific Reports 7: 40325

  7. Hensley, M. R., Chua, R. F., Leung, Y. F., Yang, J. Y., Zhang, G. (2016) Molecular Evolution of MDM1, a "Duplication-Resistant" Gene in Vertebrates. PLoS One 11, e0163229, doi:10.1371/journal.pone.0163229.

  8. Hensley, M.R., Cui, Z., Chua, R.F.M., Simpson, S., Shammas, N.L., Yang, J.-Y., Leung, Y.F., and Zhang, G. (2016). Evolutionary and developmental analysis reveals KANK genes were co-opted for vertebrate vascular development. Scientific Reports 6, 27816.

  9. Tarazona, O.A., Slota, L.A., Lopez, D.H., Zhang, G. & Cohn, M.J. (2016) The genetic program for cartilage development has deep homology within Bilateria. Nature, 533: 86–89.Z

  10. Li, Y.H., Luo, J., Mosley, Y.Y., Hedrick, V.E., Paul, L.N., Chang, J., Zhang, G., Wang, Y.K., Banko, M.R., Brunet, A., Kuang, S., Wu, J.L., Chang, C.J., Scott, M.P., Yang, J.Y. (2015). AMP-Activated Protein Kinase Directly Phosphorylates and Destabilizes Hedgehog Pathway Transcription Factor GLI1 in Medulloblastoma. Cell Reports 12, 599-609.

  11. Zhang G., Yang J.Y, Cui Z.B. (2015) New Insight into Cancer Aneuploidy in Zebrafish. International Review of Cell and Molecular Biology, 314: 149-170.

  12. Zhang G., Hoersch S., Amsterdam A., Whittaker C.A., Beert E., Catchen, J.M., Farrington, S., Postlethwait, J.H., Legius E., Hopkins, N., Lees, J.A. (2013) Comparative Oncogenomic Analysis of Copy Number Alterations in Human and Zebrafish Tumors Enables Cancer Driver Discovery. PLoS Genetics 9(8): e1003734. doi:10.1371/journal.pgen.1003734

  13. Zhang G., Vemulapalli, T.H., Yang J.Y. (2013) Phylooncogenomics: Examining the cancer genome in the context of vertebrate evolution. Applied & Translational Genomics, 2: 48-54.

  14. Zhang G., Hoersch S., Amsterdam A., Whittaker C.A,. Lees J.A., Hopkins N. (2010). Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers. Proceedings of the National Academy of Sciences, 107: 16940–16945.

  15. Zhang, G. (2009). An Evo-Devo view on the origin of the backbone: evolutionary development of the vertebrae. Integrative and Comparative Biology 49: 178-186.

  16. Zhang, G. Eames, B.F. and Cohn, M.J. (2009).  Evolution of Vertebrate Cartilage Development.  Current Topics in Developmental Biology 86: 15-42.

  17. Zhang, G. and Cohn, M.J. (2008). Genome duplication and the origin of the vertebrate skeleton. Current Opinion in Genetics & Development, 18:387–393.

  18. Freitas, R., Zhang, G. and Cohn, M. J (2007).  Multiphasic expression of HoxA and HoxD genes during shark fin development: implications for the origin of tetrapod limbs. PLoS ONE, 2: e754.

  19. Zhang, G. and Cohn, M.J. (2006). Hagfish and lancelet fibrillar collagens reveal that type II collagen-based cartilage evolved in stem vertebrates. Proceedings of the National Academy of Sciences, 103: 16829-33.

  20. Freitas, R., Zhang, G., Cohn, M.J. (2006). Evidence that mechanisms of fin development evolved in the midline of early vertebrates. Nature. 2006 442: 1033-7.

  21. Zhang, G., Miyamoto, M.M., Cohn, M.J. (2006). Lamprey type II collagen and Sox9 reveal an ancient origin of the vertebrate collagenous skeleton. Proceedings of the National Academy of Sciences, 103: 3180-5.

  22. Freitas, R., Zhang, G., Albert, J.S., Evans, D.H., Cohn, M.J. (2006). Developmental origin of shark electrosensory organs. Evolution and Development.8: 74-80.

  23. Zhang, G., Chen, Q., Qiu, C.P., Xia, M.Y. (2002). Sequence Analysis of rDNA-LSU Gene of Orientobilharzia turkestanicum from Mainland of China. Chinese Journal of Parasitology and Parasitic Diseases. 20: 86-9. (In Chinese)

  24. Zhang, G., Qiu, C.P., Qiu, D.C., Xia, M.Y. (2002). Study on molecular phylogeny of Schistosoma sinensium based on mitochondrial genes. Chinese Journal of Parasitology and Parasitic Diseases. 20: 10-3. (In Chinese)

  25. Zhang, G., Olivier, V., Qiu, C.P., Jourdane, J., Xia, M.Y.  (2001). Afrique or Asie, quelle est l'origine evolutive des schistosomes humains? C. R. Acad. Sci. Paris, Sciences de la vie/Life Sciences. 324: 1001-1010. (In French)

  26. Zhang, G., Qiu, C.P., Xia, M.Y. (2001). Research Progress of Schistosoma sinensium. Chinese Journal of Zoonosis. 17: 92-97. (In Chinese)

  27. Wang, C.R., Zhang, G., Wang, W.J., Xu, C.B., Yu, W.C., Qiu, J.H., Xu, L.M., Shen, B.G., Xia, M.Y. (2001) Scanning electron microscopic study of the integumental surface of adult Orientobilharzia cheni.  Chinese Journal of Zoonosis. 17(2): 59-63. (In Chinese)

  28. Zhang, G., Qiu, D.C., Wang, C.R., Xia, M.Y. (2001). Scanning electron microscopy of the tegument of the adult Schistosoma sinensium and Orientobilharzia turkestanicum var. tuberculata and comparison with other schistosomes. Chinese Journal of Verterinary Parasitology. 3: 1-5. (In Chinese)

  29. Zhang, G., Qiu, C.P., Qiu, D.C., Chang, Z.S., Qin, Z.H., Xia, M.Y. (2001). Study on molecular phylogeny of Schistosoma sinensium based on nuclear ribosomal DNA. Chinese Journal of Parasitology and Parasitic Diseases. 19: 201-204. (In Chinese)

  30. Zhang, G., Xia, M.Y. (2000). Progress of the schistosome genomics. Foreign Medical Science, Parasitology. 27: 212-217. (In Chinese)

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