Publications

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Current Publications

- S. Hammad, M. El-Gazzar, N. Abutaleb, D. Li, I. Ramming, A. Shekhar, M. Abdel-Halim, E. Elrazaz, M. N. Seleem, U. Bilitewski, K. Abouzid, E. El-Hossary. (2019). Synthesis and Antimicrobial Evaluation of New Halogenated 1,3-Thiazolidin-4-ones. Bioorganic Chemistry.2019.103517

- H. Mohammad, H. Eldesouky, T. Hazbun, A. Mayhoub, M. N. Seleem. (2019). Identification of a Phenylthiazole Small Molecule with Dual Antifungal and Antibiofilm Activity Against Candida albicans and Candida auris. Scientific Reports 9 (1), 1-12

- AS Mancy, N. Abutaleb, M. Elsebaei, A. Yossef Saad, A. Kotb, A. Ali, J. A Abdel-Aleem, H. Mohammad, M. N. Seleem, A. Mayhoub. (2019). Balancing Physicochemical Properties of Phenylthiazole Compounds with Antibacterial Potency by Modifying the Lipophilic Side Chain. ACS infectious diseases. acsinfecdis.9b00211

- G. Naclerio, N. Abutaleb, K. Onyedibe, M. N. Seleem and H. Sintim. (2019). Potent trifluoromethoxy, trifluoromethylsulfonyl, trifluoromethylthio and pentafluorosulfanyl containing (1,3,4-oxadiazol-2-yl)benzamides against drug-resistant Gram-positive bacteria. 10.1039/C9MD00391F

- D. Mody, A. Athamneh, & M. N. Seleem. (2019). Curcumin: A natural derivative with antibacterial activity against Clostridium difficile. Journal of Global Antimicrobial Resistance. 2019 Oct 14. pii: S2213-7165(19)30259-0. PubMed PMID: 316226839

- N. S. Abutaleb & M. N. Seleem. (2019). Antivirulence activity of auranofin against vancomycin-resistant enterococci: in vitro and in vivo studies. International Journal of Antimicrobial Agents. 26 October 2019. PMID:31669742

- Y. Hosny, N. S. Abutaleb, M. Omara, M. Alhashimi, M. Elsebaei, H. Elzahabi, M. N. Seleem, A. Mayhoub. (2019). Modifying the lipophilic part of phenylthiazole antibiotics to control their drug-likeness. European Journal of Medicinal Chemistry. 31 October 2019, 111830.

- S. Al-Trawneh, S. Al-Dawdieh, N. S. Abutaleb, A. Tarawneh, E. Salama, M. El-Abadelah, & M. N. Seleem. (2019). Synthesis of new pyrazolo[5,1-c][1,2,4]triazines with antifungal and antibiofilm activities. Chem. Pap. (2019).

- E. Doklaa, N. S. Abutaleb, S. Milik, D. Li, K. Elbaza, M. Shalaby, R. Al-Karaki, M. Nasr, C. Klein, K. Abouzid, M. N. Seleem. (2019). Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteria. European Journal of Medicinal Chemistry. 5 November 2019, 111850.

- M. Alhashimi, A. Mayhoub & M. N. Seleem. (2019). Repurposing salicylamide for combating multidrug-resistant Neisseria gonorrhoeae. Antimicrobial Agents and Chemotherapy. 10.1128/AAC.01225-19

- X. Shao, A. Abdelkhalek, N. Abutaleb, U. Velagapudi M. N. Seleem & T. Talele. (2019). Chemical space exploration around thieno[3,2-d]pyrimidin-4(3H)-one scaffold led to a novel class of highly active Clostridium difficile inhibitors. Journal of Medicinal Chemistry. jm-2019-01198f.

- M. Elsebaei, N. Abutaleb, Abdulrahman Mahgoub, D. Li, M. Hagras, H. Mohammad, M. N. Seleem & A. Mayhoub. (2019). Phenylthiazoles with Nitrogenous Side Chain: An Approach to Overcome Molecular Obesity. European Journal of Medicinal Chemistry. (182)- 111593.

- N. Dayal, C. Opoku-Temeng, H. Mohammad, N. S. Abutaleb, D. Hernandez, M. N. Seleem & H. Sintim. (2019). Inhibitors of Intracellular Gram-positive Bacteria Growth Synthesized via Povarov-Doebner Reactions. ACS Infectious Diseases. doi.org/10.1021/acsinfecdis.9b00022.

- B. Sloan, H. Mohammad, N. S. Abutaleb & M. N. Seleem. (2019). Comparison between a novel tap water wound irrigation device and a sterile saline device in an animal model. Trauma. 2019-3-1-6

- Hammad, N. S. Abutaleb, M. Elsebaei, M. Ali, M. Al-Sawah, M. N. Seleem & A. Mayhoub. (2019). From phenylthiazoles to phenylpyrazoles: Broaden the antibacterial spectrum towards carbapenam-resistant strains. Journal of Medicinal Chemistry. 62 (17), 7998-8010

- M. Elsebaei, H. Mohammad, , A. Samir, N. S. Abutaleb, A. Norvil, A. Michie, M. Mostafa, H. Gowher, M. N. Seleem & A. Mayhoub. (2019). Lipophilic efficient phenylthiazoles with potent undecaprenyl pyrophosphatase inhibitory activity. European Journal of Medicinal Chemistry. 175 (1) 49-62.

 - H. Mohammad, K. Kyei-Baffoura, N. Abutaleb, M. Dai & M. N. Seleem (2019). An aryl isonitrile compound with an improved physicochemical profile that is effective in two mouse models of multidrug-resistant Staphylococcus aureus infection. Journal of Global Antimicrobial Resistance. 7165(19)30105-5.

- K. Kyei-Baffoura, H. Mohammad, M. N. Seleem & M. Dai. (2019). Second-generation aryl isonitrile compounds targeting multidrug-resistant Staphylococcus aureus. Bioorganic & Medicinal Chemistry 27 (2019):1845-54.

- S. Malwal, L. Chen, H. Hicks, F. Qu, W. Liu, A. Shillo, W. Law, J. Zhang, N. Chandnani, X. Han, Y. Zheng, C. Chen, R. Guo, A. AbdelKhalek, M. N. Seleem & E. Oldfield. (2019). Discovery of lipophilic bisphosphonates that target bacterial cell wall and quinone biosynthesis. Journal of Medicinal Chemistry 62 (5), pp 2564–2581.

- Kotb, N. S. Abutaleb, M. Hagras, A. Bayoumi, M. Mohamed, A. Moustafa, A. Ghiaty, M. N. Seleem & A. Mayhoub. (2019). tert-Butylphenylthiazoles with oxadiazole linker: A novel orally bioavailable class of antibiotics exhibiting antibiofilm activity. RSC Advances 9(12):6770-6778.

- Abdelkhalek A., N. Abutaleb, H. Mohammad & M. N. Seleem. (2019). Antibacterial and antivirulence activities of auranofin against Clostridium difficile. International Journal of Antimicrobial Agents 53: 54-62.

- P. Dong, H. Mohammad, X. Wang, J. Hui, J. Li, L. Liang, M. N. Seleem & Ji-Xin Cheng. (2019). Photolysis of staphyloxanthin in methicillin-resistant Staphylococcus aureus potentiates killing by reactive oxygen species. Advanced Science. DOI: 10.1002/advs.201900030

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