Christoph Konradt, PhD

Assistant Professor

Department of Comparative Pathobiology

Purdue University College of Veterinary Medicine
625 Harrison Street
West Lafayette, IN 47907

Phone: 765.496.3455
Email: ckonradt@purdue.edu

Konradt Lab

Education

2011 - PhD | Institut Pasteur, France / University of Würzburg, Germany
2005 - MS | University of Hohenheim, Germany

Areas of Interest

The role of endothelial and T cells during infections of the vascular compartment
Immune responses at the maternal-fetal interface during infection

Selected Publications

– Konradt C, Frigimelica E, Nothelfer K, Puhar A, Salgado-Pabon W, di Bartolo V, Scott-Algara D, Rodrigues CD, Sansonetti PJ, Phalipon A. The Shigella flexneri type three secretion system effector IpgD inhibits T cell migration by manipulating host phosphoinositide metabolism. Cell Host Microbe. 2011 Apr 21;9(4):263-72.

– Harris TH, Banigan EJ, Christian DA, Konradt C, Tait Wojno ED, Norose K, Wilson EH, John B, Weninger W, Luster AD, Liu AJ, Hunter CA. Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells. Nature. 2012 Jun 28;486(7404) :545-8.

– Konradt C, Ueno N, Christian DA, Delong J, Harms Pritchard G, Herz J,Bzik DJ, Koshy AA, McGavern DB, Lodoen MB, Hunter CA. Endothelial cells are a replicative niche for entry Toxoplasma gondii to the central nervous system. Nature Microbiology. 2016; 1:16001.

– Weinkopff T, Konradt C, Christian DA, Discher DE, Hunter CA and Scott P. Leishmania major Infection-Induced VEGF-A/VEGFR-2 Signaling Promotes Lymphangiogenesis That Controls Disease. The Journal of Immunology 197, 1823–1831 (2016).

– O’Brien CA, Overall C, Konradt C, O’Hara Hall AC, Hayes NW, Wagage S, et al. CD11c-Expressing Cells Affect Regulatory T Cell Behavior in the Meninges during Central Nervous System Infection. The Journal of Immunology. 2017 May 15;198(10):4054–61.

– Glatman Zaretsky A*, Konradt C*, Dépis F, Wing JB, Goenka R, Gomez Atria D, Silver JS, Cho S, Wolf AI, Quinn WJ, Engiles JB, Brown DC, Beiting D, Erikson J, Allman D, Cancro MP, Sakaguchi S, Lu L, Benoist CO, Hunter CA. T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow. Cell Reports 18, 1906–1916 (2017).

– Konradt C, Hunter CA. Pathogen interactions with endothelial cells and the induction of innate and adaptive immunity. Eur. J. Immunol. 2018 Sep 21;48(10):1607–20.

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