BMS Faculty Research Interests

  • Dr. Ourania Andrisani — Cancer biology; virus-induced liver cancer; prostate cancer; chromatin remodeling and microRNAs in cell growth and differentiation.
    • Current Projects — Investigating molecular mechanisms of cancer pathogenesis and development of strategies for mechanism-based therapy.
  • Dr. Elikplimi Asem — Regulation of ovarian function; basement membrane function.
  • Dr. Marxa Figueiredo - Osteoimmunology; gene and drug delivery for modulating interactions between bone and immune system for treating cancer and arthritis.
    • Current Projects - 1) Gene delivery, using ultrasound-mediated sonoporation strategies to express targeted osteo-immune cytokines for restoring bone and immune cell homeostasis; 2) Stem cell delivery, exploring the therapeutic ability of adipose-derived mesenchymal/stromal stem cells to deliver the pro-osteogeneic and antiangiogenic Pigment Epithelium-Derived Factor; 3) Role of small molecules for pharmacological interventions for mediating joint cartilage and bone repair.
  • Dr. Kevin HannonInstructional technology.
    • Current Projects Delivering anatomical content in interactive mobile formats.
  • Dr. Laurie JaegerPeri-implantation conceptus development; conceptus-maternal communication.
    • Current Projects Mechanisms of calcium influx during development and its effect on normal conceptus development; the roles of beta transforming growth factors and integrins during pre-implanatation development and placentation.
  • Dr. Sophie Lelièvre  Cell nucleus organization and function in normal and cancer cells; mechanisms of risk and primary prevention of cancer; 3D cell culture and organs-on-chip models.
    • Current Projects  Role of nuclear structural protein NuMA in chromatin organization and stress response; mechanisms associated with the control of chromatin organization and cell behavior by the nuclear shape; mechanisms and chromatin-related targets involved in the progression of triple negative breast cancer; development of disease on-a-chip platforms for anticancer drug screening; development of risk-on-a-chip platforms for environmental epigenetics screening.
  • Dr. Russell MainIn vivo musculoskeletal biomechanics; skeletal adaptation; biological regulation of skeletal structure and mass.
    • Current Projects How regulation of bone at the genetic and cellular level affects skeletal structure and the ability to withstand mechanical load; in vivo biomechanics to measure how the musculoskeletal system is loaded by external forces during locomotion; musculoskeletal adaptation to applied mechanical loading and unloading at the gene, protein, cell, and whole bone levels.
  • Dr. Susan MendrysaTumor suppressor, p53; oncogene, MDM2; cancer cell biology; pediatric brain cancer; regulation of cell fate decisions; cerebellar development.
    • Current projects Elucidating the role of MDM2, a critical negative regulator of the p53 tumor suppressor, in cerebellar development and tumorigenesis; exploiting genetically modified mice in combination with cell culture models to place MDM2 and p53 within the molecular signaling pathways that govern neuronal differentiation and cell fate decisions.
  • Dr. Abdelfattah NourInteractive and e-learning; food security in poor households; physiological biomarkers; growth and development.
    • Current Projects — Educational research focus on information literacy, team-based learning (e.g. Study the Effectiveness of Implementing Team Building Strategies Program for Nursing-Interns by Using Team- Based), social networking and learning; effectiveness of teaching the clinical administrative course by using computer-based training in developing nurse intern administrative knowledge and skills; Small ruminants for food security in poor households in Africa: The role of women's cooperatives and entrepreneurship; effects of drug-induced renal damage on CBC, biochemical profile of the serum, and kidneys histopathological changes in experimental rats; study of the possible association between some of the uremic toxins and allergic factors in hemodialysis patients suffering from pruritus; histological and ultra-structural studies of the major endocrine glands of Nile tilapia (in relation to Age and Weight).
  • Dr. J. Paul RobinsonDevelopment of diagnostic tools that focus on cervical cancer; strong program in high content screening in the area of bioengineering; cytomic-bioengineering interface.
    • Current Projects —Creating new tools for the cellular and molecular screening for cervical cancer using cell sorting and multiplexed PCR with the goal of identifying better diagnostics as well as prognostic value; Using new approaches to high throughput and very high content analysis of cellular function; Interest in developing low cost technologies for resource limited regions.
  • Dr. John TurekMechanisms of connective tissue healing (ligaments and bone); electron microscopy and image analysis; novel imaging/spectral methods (motility contrast imaging/tissue dynamics spectroscopy) for tissue based drug screening and toxicology.
    • Current Projects Development of tissue dynamic spectroscopy for high-throughput, high-content tissue based drug screening; tissue dynamic spectroscopy as a predictor of chemotherapeutic response in ovarian cancer; tissue dynamic spectroscopy for ovum and embryo viability assessment.
  • Dr. James WalkerMedical education.

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