Dielectric/Impedance Spectroscopy for in-line measurement of moisture content DUIRI - Discovery Undergraduate Interdisciplinary Research Internship Summer 2023 Accepted Materials engineering, Sensor design, Data processing/machine learning Moisture content is a critical property of pharmaceutical products. A calibration-free testing method to measure the moisture content during in-line manufacturing could accelerate the pharmaceutical materials' R&D and production capacity. A novel moisture content measurement with less calibration requirement will provide a faster yet accurate way to determine moisture content across various industries such as pharmaceuticals, food, energy, and biotechnology. This project will systematically investigate the feasibility of developing a calibration-free moisture content measurement method for pharmaceutical materials (powder, solid, etc.) using impedance/dielectric spectroscopy. The goal is to establish a scientific framework that enables the future development of a direct testing method of moisture content with minimum to zero calibration that could be practically implemented in a container or a line of continuous pharmaceutical powder manufacturing systems. Yining Feng Guangshuai Han 1. Learn and investigate the sensor design.
2. Perform electrical characteristic testing on pharmaceutical materials.
3. Conduct machine learning data processing and develop the mathematical model.
GPA>3.2. Basic knowledge of electricity and chemistry. Applicants with experience in materials characterization, electrical testing, spectroscopy testing, and data analysis are preferred. 0 40 (estimated)

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