Software Development for Cardiovascular Image Analysis in Duchenne Muscular Dystrophy
DUIRI - Discovery Undergraduate Interdisciplinary Research Internship
Spring 2025
Accepted
Biomedical engineering, cardiovascular imaging
Duchenne Muscular Dystrophy (DMD) is a recessive progressive neuromuscular disease that predominantly affects boys. Cardiovascular complications are the leading cause of death in these patients, and early identification of cardiac muscle impairment is critical, as it enables timely prophylactic treatment with cardioprotective medications. The goal of this project is to enhance cardiac disease diagnosis and monitoring in DMD by developing software to analyze images from different modalities, such as 4D (3D + time) Ultrasound and Magnetic Resonance Imaging. Our aim is to provide clinicians with tools for early intervention, as well as enable complex analysis frameworks in research environments, furthering the understanding of cardiovascular mechanics.
Marco Aurelio Conde Oliveira Prado
Marco Aurelio Conde Oliveira Prado
Students assisting with this project would be working on the development of medical image analysis software. Tasks include designing graphical user interfaces for end-users, creating image analysis scripts and developing machine learning models for image segmentation and disease progression prediction.
https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds)#:~:text=Cardiovascular%20diseases%20(CVDs)%20are%20the,%2D%20and%20middle%2Dincome%20countries.
https://engineering.purdue.edu/cvirl
Students should be interested in imaging research. Previous programming experience is required, although proficiency in a specific language or framework is not mandatory. A basic understanding of cardiovascular anatomy will be helpful but is not necessary.
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5 (estimated)